Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942850 | 0.92 | ALDH1A1 (0.48) | TSHRTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL28671641 | 0.89 | TSHR (0.47) | TSHRTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL24766789 | 0.86 | ALDH1A1 (0.44) | TSHRTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL14646722 | 0.84 | TSHR (0.43) | TSHRTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL12769833 | 0.84 | ALDH1A1 (0.54) | TSHRTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL18107365 | 0.84 | LMNA (0.48) | TSHRTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL1991323 | 0.84 | LMNA (0.54) | TSHRTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL29044390 | 0.83 | — | — | |
| SCHEMBL29044388 | 0.83 | — | — | |
| SCHEMBL19006859 | 0.81 | LMNA (0.56) | TSHRALDH1A1LMNADNM1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107540867-A | Polysulfide sealants for the chemical blowing of aviation fuel case | 波音公司 | 2018-01-05 | — | — | CN | disclosed |
| US-20080312404-A1 | Novel diepoxides and epoxy resins | PEWS R GARTH | 2008-12-18 | — | — | US | disclosed |
| US-7462728-B2 | Diepoxide derivatives of N,N*-disubstituted disulfonamides | PEWS R GARTH | 2008-12-09 | — | — | US | disclosed |
| US-7141684-B2 | Diepoxide derivatives of diallyl phenolics | PEWS R GARTH | 2006-11-28 | — | — | US | disclosed |
| US-20060128978-A1 | Diepoxide derivatives of N, N*-disubstituted disulfonamides | PEWS R G | 2006-06-15 | — | — | US | disclosed |
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | PEWS R G (US) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090673-A1 | Novel diepoxide derivatives of diallyl phenolics | EBP, EED, ESR2 | TSHR 4303/4885TDP1 4097/4885ALDH1A1 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.