Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568717 | 0.97 | LMNA (0.56) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL9793319 | 0.97 | LMNA (0.56) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL1989581 | 0.97 | LMNA (0.56) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL16781423 | 0.97 | LMNA (0.56) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL1996950 | 0.97 | LMNA (0.56) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL7614261 | 0.97 | LMNA (0.56) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL19006859 | 0.97 | LMNA (0.56) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL13677562 | 0.92 | LMNA (0.52) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL17546729 | 0.92 | LMNA (0.52) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL12942850 | 0.92 | ALDH1A1 (0.48) | LMNADNM1ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208059-B2 | Heterocyclic modulators of HIF activity for treatment of disease | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-02-19 | — | — | US | disclosed |
| CN-104395274-B | Alkylated diphenyl ethers compound and the lubricating oils containing the compound | 株式会社MORESCO | 2017-12-05 | — | — | CN | disclosed |
| US-20170121342-A1 | HETEROCYCLIC MODULATORS OF HIF ACTIVITY FOR TREATMENT OF DISEASE | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM | 2017-05-04 | — | — | US | disclosed |
| US-9561992-B2 | Alkylated diphenyl ether compound and lubricating oil containing said compound | MORESCO CORPORATION (JP) | 2017-02-07 | — | — | US | disclosed |
| CN-104507900-B | Alkylated diphenyl ethers compound and the lubricating oils containing this compound | 株式会社MORESCO | 2016-06-08 | — | — | CN | disclosed |
| US-9309481-B2 | Lubricant composition | IDEMITSU KOSAN CO., LTD. (JP) | 2016-04-12 | — | — | US | disclosed |
| US-20150225327-A1 | ALKYLATED DIPHENYL ETHER COMPOUND AND LUBRICATING OIL CONTAINING SAID COMPOUND | MORESCO CORPORATION (JP) | 2015-08-13 | — | — | US | disclosed |
| US-9074158-B2 | Detergent-dispersant, additive composition for lubricant, and lubricant composition | IDEMITSU KOSAN CO., LTD. (JP) | 2015-07-07 | — | — | US | disclosed |
| US-20150166447-A1 | ALKYLATED DIPHENYL ETHER COMPOUND AND LUBRICATING OIL CONTAINING SAID COMPOUND | MORESCO CORPORATION (JP) | 2015-06-18 | — | — | US | disclosed |
| CN-102782103-B | Lubricating oil composition | IDEMITSU KOSAN CO | 2015-04-29 | — | — | CN | disclosed |
| US-20130005624-A1 | LUBRICANT COMPOSITION | IDEMITSU KOSAN CO., LTD. (JP) | 2013-01-03 | — | — | US | disclosed |
| CN-102782103-A | lubricating oil composition | IDEMITSU KOSAN CO | 2012-11-14 | — | — | CN | disclosed |
| EP-2520638-A1 | Anti-wear agent, additive composition for lubricant, and lubricant composition | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-20110152145-A1 | ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION | IDEMITSU KOSAN CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| US-20100184982-A1 | DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION | IDEMITSU KOSAN CO., LTD (JP) | 2010-07-22 | — | — | US | disclosed |
| CN-101778932-A | Anti-wear agent, additive composition for lubricant, and lubricating oil composition | IDEMITSU KOSAN CO | 2010-07-14 | — | — | CN | disclosed |
| EP-2177594-A1 | ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION | Idemitsu Kosan Co., Ltd. (JP) | 2010-04-21 | — | — | EP | disclosed |
| CN-101679898-A | Detergent dispersant, additive composition for lubricant, and lubricating oil composition | IDEMITSU KOSAN CO | 2010-03-24 | — | — | CN | disclosed |
| EP-2161324-A1 | DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION | Idemitsu Kosan Co., Ltd. (JP) | 2010-03-10 | — | — | EP | disclosed |
| US-7592392-B2 | Synthesis of functional polymers for use in organic synthesis and combinatorial chemistry | MERCK & CO. INC. (US) | 2009-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225327-A1 | ALKYLATED DIPHENYL ETHER COMPOUND AND LUBRICATING OIL CONTAINING SAID COMPOUND | C9, OR10J3, NR0B2 | LMNA 2029/4885DNM1 1347/4885ALDH1A1 2947/4885 |
| US-20100184982-A1 | DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION | DSC1, DSP, CDC73 | LMNA 3367/4885DNM1 1180/4885ALDH1A1 3038/4885 |
| US-10208059-B2 | Heterocyclic modulators of HIF activity for treatment of disease | HIF1AN, HIF1A, EGLN3 | LMNA 3216/4885DNM1 2681/4885ALDH1A1 546/4885 |
| US-20150166447-A1 | ALKYLATED DIPHENYL ETHER COMPOUND AND LUBRICATING OIL CONTAINING SAID COMPOUND | EBP, NR2C2, NR0B2 | LMNA 3019/4885DNM1 956/4885ALDH1A1 3037/4885 |
| US-20170121342-A1 | HETEROCYCLIC MODULATORS OF HIF ACTIVITY FOR TREATMENT OF DISEASE | HIF1AN, HIF1A, EGLN3 | LMNA 3216/4885DNM1 2681/4885ALDH1A1 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.