Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498377 | 0.90 | ALDH1A1 (0.56) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL18380932 | 0.83 | SCN5A (0.56) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL2341418 | 0.82 | MEN1 (0.42) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL25144902 | 0.82 | CYP1A2 (0.43) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL2037249 | 0.79 | ALDH1A1 (0.47) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7026279 | 0.79 | ALDH1A1 (0.47) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9682 | 0.79 | MAPT (0.63) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1710060 | 0.79 | NPC1 (0.47) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL2259946 | 0.79 | CA12 (0.50) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9458453 | 0.79 | APP (0.50) | MAPTMEN1LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080015-A2 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON, INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20040220409-A1 | Flecainide synthesis | MCDANIEL WILLIAM C | 2004-11-04 | — | — | US | disclosed |
| WO-2002066413-A1 | FLECAINIDE SYNTHESIS | NARCHEM CORPORATION (US) | 2002-08-29 | — | — | WO | disclosed |
| US-4816596-A | ETHERIFICATION OR SULFIDING A PHENOL OR THIOPHENOL | RHONE-POLENC SPECIALITES CHIMOUES (FR) | 1989-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220409-A1 | Flecainide synthesis | KCNH1, CYP3A43, CYP2F1 | MAPT 4170/4885MEN1 3933/4885LMNA 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.