Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673691 | 0.89 | CREBBP (0.50) | CREBBPTP53TSHRKMT2AHTT | |
| SCHEMBL2945858 | 0.84 | CREBBP (0.49) | CREBBPTP53TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL4585032 | 0.83 | CREBBP (0.46) | CREBBPKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL19159666 | 0.81 | CREBBP (0.45) | CREBBPKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL21384072 | 0.81 | CREBBP (0.45) | CREBBPKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL709323 | 0.81 | BRD4 (0.47) | CREBBPKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL28300808 | 0.81 | BRD4 (0.47) | CREBBPKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL13890744 | 0.79 | KDM4E (0.46) | CREBBPKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL13702366 | 0.78 | BRD4 (0.54) | CREBBPTSHRKMT2AHTTMEN1 | |
| SCHEMBL2034671 | 0.78 | LMNA (0.51) | CREBBPTSHRKMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112806-A1 | GENERATION AND USE OF EPIGENETIC MAPS FOR DRUG DISCOVERY | MOONWALK BIOSCIENCES, INC. (US) | 2024-05-30 | — | — | WO | claimed |
| EP-3174852-B1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | ABAC THERAPEUTICS S L (ES) | 2018-07-18 | — | — | EP | claimed |
| US-9840467-B2 | Arylhydrazides containing a 2-pyridone moiety as selective antibacterial agents | ABAC Therapeutics, S.L. (ES) | 2017-12-12 | — | — | US | claimed |
| US-20170217887-A1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | ABAC Therapeutics, S.L. (ES) | 2017-08-03 | — | — | US | claimed |
| EP-3174852-A1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | ABAC THERAPEUTICS, S.L. (ES) | 2017-06-07 | — | — | EP | claimed |
| WO-2016016291-A1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2016-02-04 | — | — | WO | claimed |
| US-8524774-B1 | Topical two step polytherapy for treatment of psoriasis and other skin disorders | CYMBIOTICS, INC. (US) | 2013-09-03 | — | — | US | claimed |
| US-20100048579-A1 | PYRIDAZINE-, PYRIDINE- AND PYRANE-DERIVATIVES AS GPBAR1 AGONISTS | ARISTA LUCA | 2010-02-25 | — | — | US | claimed |
| EP-2146970-A1 | PYRIDAZINE-, PYRIDINE- AND PYRANE-DERIVATIVES AS GPBAR1 AGONISIS | Novartis Ag (CH) | 2010-01-27 | — | — | EP | claimed |
| WO-2008125627-A1 | PYRIDAZINE-, PYRIDINE- AND PYRANE-DERIVATIVES AS GPBAR1 AGONISIS | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | claimed |
| US-4258052-A | APPLYING TOPICALLY | YU RUEY J | 1981-03-24 | — | — | US | claimed |
| EP-4737449-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| EP-4727599-A2 | POLY(OXAZOLINE) CONJUGATES WITH PENDANT CATIONIC GROUPS AND LIPID NANOPARTICLES AND POLYPLEXES INCLUDING SAME | Serina Therapeutics (AL), Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4727939-A1 | 5-(CINNOLIN-6-YL)THIAZOLE COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2026-04-22 | — | — | EP | disclosed |
| EP-4713306-A1 | NOVEL TRACER FOR THE IN VIVO DETECTION OF THE AGGREGATION OF ALPHA-SYNUCLEIN | Stichting Amsterdam UMC (NL) | 2026-03-25 | — | — | EP | disclosed |
| WO-2004031175-A2 | N-SUBSTITUTED-2-OXODIHYDROPYRIDINE DERIVATIVES AS NPY ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-04-15 | — | — | WO | disclosed |
| US-20030216758-A1 | Coated surgical patches | ANGIOTECH PHARMACEUTICALS, INC. (CA) | 2003-11-20 | — | — | US | disclosed |
| US-20030144570-A1 | Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors | ANGIOTECH PHARMACEUTICALS, INC. (CA) | 2003-07-31 | — | — | US | disclosed |
| US-20020055666-A1 | Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors | ANGIOTECH INTERNATIONAL AG (CH) | 2002-05-09 | — | — | US | disclosed |
| US-4258052-A | APPLYING TOPICALLY | YU RUEY J | 1981-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217887-A1 | ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS | ABCC5, AAAS, PDXK | CREBBP 747/4885TP53 4762/4885TSHR 3550/4885 |
| US-20100048579-A1 | PYRIDAZINE-, PYRIDINE- AND PYRANE-DERIVATIVES AS GPBAR1 AGONISTS | GPBAR1, GPER1, ADRB1 | CREBBP 2067/4885TP53 3360/4885TSHR 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.