Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.59 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.45 |
| ▸ | DUT | P33316 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264133 | 0.91 | KIF11 (0.68) | KIF11KCNN4SIGMAR1DUT | |
| SCHEMBL6251086 | 0.90 | KIF11 (0.57) | KIF11KCNN4SIGMAR1DUTCHRM2 | |
| SCHEMBL29679194 | 0.85 | KIF11 (0.65) | KIF11KCNN4SIGMAR1DUTCHRM2 | |
| SCHEMBL9472251 | 0.83 | DRD4 (0.69) | — | |
| SCHEMBL12264131 | 0.82 | KIF11 (0.74) | KIF11KCNN4DUT | |
| SCHEMBL2283152 | 0.82 | KIF11 (0.74) | KIF11KCNN4DUTCHRM2GRIN1 | |
| SCHEMBL3684180 | 0.82 | KIF11 (0.57) | KIF11KCNN4DUT | |
| SCHEMBL20644264 | 0.82 | KCNN4 (0.61) | KIF11KCNN4SIGMAR1DUT | |
| SCHEMBL9617559 | 0.80 | KIF11 (0.78) | KIF11KCNN4SIGMAR1DUT | |
| SCHEMBL14286703 | 0.80 | KIF11 (0.55) | KIF11KCNN4DUTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425579-B2 | Methods for inhibiting activity of polyamine transporters | UNIVERSITE LAVAL (CA) | 2008-09-16 | — | — | US | disclosed |
| US-20050267220-A1 | Methods for inhibiting activity of polyamine transporters | UNIVERSITE LAVAL (CA) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267220-A1 | Methods for inhibiting activity of polyamine transporters | SLC7A1, SLC6A7, SLC1A5 | KIF11 3950/4885KCNN4 2007/4885SIGMAR1 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.