Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 2/20 | 0.48 |
| ▸ | FNTB | P49356 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917724 | 0.86 | MAPT (0.66) | NR4A1SRD5A2ALDH1A1POLBGAA | |
| SCHEMBL26187139 | 0.83 | AKR1C3 (0.62) | SRD5A2ALDH1A1POLBGAAMAPT | |
| SCHEMBL1820530 | 0.83 | NR4A1 (0.66) | NR4A1SRD5A2ALDH1A1POLBGAA | |
| SCHEMBL4551433 | 0.80 | NR4A1 (0.62) | NR4A1SRD5A2ALDH1A1GAAFNTA | |
| SCHEMBL30038107 | 0.80 | MEN1 (0.52) | ALDH1A1POLBGAAMAPTMMP2 | |
| SCHEMBL1821327 | 0.80 | NR4A1 (0.62) | NR4A1SRD5A2ALDH1A1GAAFNTA | |
| SCHEMBL1246659 | 0.80 | NR4A1 (0.62) | NR4A1SRD5A2ALDH1A1GAAFNTA | |
| SCHEMBL5056823 | 0.80 | ALDH1A1 (0.58) | ALDH1A1POLBGAAMAPTMMP2 | |
| SCHEMBL29583954 | 0.80 | NR4A1 (0.62) | NR4A1SRD5A2ALDH1A1GAAFNTA | |
| SCHEMBL332626 | 0.79 | MAPT (0.71) | NR4A1SRD5A2ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427260-B2 | Efficient methods for solid phase synthesis using trityl chloride resins | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-09-23 | — | — | US | disclosed |
| US-20040096904-A1 | Efficient methods for solid phase synthesis using trityl chloride resins | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2004-05-20 | — | — | US | disclosed |
| WO-2002079278-A1 | EFFICIENT METHODS FOR SOLID PHASE SYNTHESIS USING TRITYL CHLORIDE RESINS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2002-10-10 | — | — | WO | disclosed |