SCHEMBL1820530

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5151524	0.89	ALDH1A1 (0.61)	NR4A1SRD5A2TSHRALDH1A1ALOX15
	SCHEMBL1819616	0.88	NR4A1 (0.69)	NR4A1SRD5A2TSHRALDH1A1ALOX15
	SCHEMBL21835148	0.86	ALDH1A1 (0.53)	NR4A1SRD5A2TSHRALDH1A1ALOX15
	SCHEMBL11850279	0.85	SRD5A2 (0.56)	NR4A1SRD5A2TSHRALDH1A1ALOX15
	SCHEMBL1821327	0.83	NR4A1 (0.62)	NR4A1SRD5A2TSHRALDH1A1FNTA
	SCHEMBL29583954	0.83	NR4A1 (0.62)	NR4A1SRD5A2TSHRALDH1A1FNTA
	SCHEMBL4801729	0.83	NR4A1 (0.62)	NR4A1SRD5A2TSHRALDH1A1FNTA
	SCHEMBL1246659	0.83	NR4A1 (0.62)	NR4A1SRD5A2TSHRALDH1A1FNTA
	SCHEMBL4551433	0.83	NR4A1 (0.62)	NR4A1SRD5A2TSHRALDH1A1FNTA
	SCHEMBL275485	0.81	TSHR (0.65)	NR4A1TSHRALDH1A1ALOX15PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.