Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.85 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.85 |
| ▸ | MEN1 | O00255 | 3/20 | 0.85 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.85 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.85 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.85 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.85 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.85 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.85 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.85 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.85 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.85 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.85 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.85 |
| ▸ | MLNR | O43193 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801745 | 0.95 | CYP2C9 (0.78) | CYP2C9CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL10724135 | 0.95 | CYP2C9 (0.78) | CYP2C9CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL7343428 | 0.94 | CYP2C9 (0.77) | CYP2C9CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL11047581 | 0.94 | CYP2C9 (0.77) | CYP2C9CYP1A2CYP3A4CYP2C19KMT2A | |
| (S)-Isradipine SCHEMBL34557 | 0.92 | CYP2C9 (1.00) | CYP2C9CYP1A2CYP3A4CYP2C19KMT2A | |
| Isradipine SCHEMBL34555 | 0.92 | CYP2C9 (1.00) | CYP2C9CYP1A2CYP3A4CYP2C19KMT2A | |
| (R)-Isradipine SCHEMBL34556 | 0.92 | CYP2C9 (1.00) | CYP2C9CYP1A2CYP3A4CYP2C19KMT2A | |
| Isradipine SCHEMBL1172992 | 0.92 | CYP2C9 (1.00) | CYP2C9CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL7341259 | 0.91 | CYP2C9 (0.73) | CYP2C9CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL7341251 | 0.90 | CYP2C9 (0.85) | CYP2C9CYP1A2CYP3A4CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329756-B2 | Process for the manufacture of Isradipine | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2008-02-12 | — | — | US | disclosed |
| US-7329756-B2 | Process for the manufacture of Isradipine | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2008-02-12 | — | — | US | disclosed |
| US-7329756-B2 | Process for the manufacture of Isradipine | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2008-02-12 | — | — | US | disclosed |
| US-20060167063-A1 | Process for the manufacture of isradipine | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167063-A1 | Process for the manufacture of isradipine | ACMSD, AASDHPPT, DDC | CYP2C9 515/4885CYP1A2 832/4885CYP3A4 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.