SCHEMBL4802446

SCHEMBL4802446

CCC[C@H]1CC[C@](c2ccc(F)cc2)(C2CCCCC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
OPRM1 P35372 1/20 0.39
SLC6A9 P48067 1/20 0.39
HSD11B1 P28845 3/20 0.38
SLC6A3 Q01959 4/20 0.37
SLC6A4 P31645 3/20 0.37
SLC6A2 P23975 2/20 0.37
TRPA1 O75762 1/20 0.35
KLK7 P49862 1/20 0.34
BCHE P06276 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4802440 1.00 CYP1A2 (0.40) CYP1A2OPRM1SLC6A9HSD11B1SLC6A3
SCHEMBL4801004 0.92 CYP1A2 (0.45) CYP1A2OPRM1SLC6A9HSD11B1SLC6A3
SCHEMBL4800998 0.92 CYP1A2 (0.45) CYP1A2OPRM1SLC6A9HSD11B1SLC6A3
SCHEMBL8435345 0.89 OPRM1 (0.41) OPRM1SLC6A9HSD11B1SLC6A3SLC6A4
SCHEMBL4800619 0.86 CYP1A2 (0.40) CYP1A2SLC6A3SLC6A4SLC6A2BCHE
SCHEMBL4800616 0.86 CYP1A2 (0.40) CYP1A2SLC6A3SLC6A4SLC6A2BCHE
SCHEMBL6524968 0.85 SLC6A4 (0.51) CYP1A2OPRM1SLC6A3SLC6A4SLC6A2
SCHEMBL4797190 0.83 SLC6A4 (0.45) SLC6A3SLC6A4SLC6A2POLB
SCHEMBL4797186 0.83 SLC6A4 (0.45) SLC6A3SLC6A4SLC6A2POLB
SCHEMBL9180980 0.82 SLC6A3 (0.40) CYP1A2OPRM1SLC6A9HSD11B1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7445818-B2 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-11-04 US disclosed
US-20070275182-A1 Matrix liquid crystal display WEBER GEORG 2007-11-29 US disclosed
US-7186447-B2 Two plane parallel support plates with frame form cell, with integrated non-linear elements for switching individual picture elements on support plates, and nematic liquid crystal mixture is present in cell, having positive dielectric anisotropy and high resistivity MERCK PATENT GMBH (DE) 2007-03-06 US disclosed
US-20050196551-A1 Matrix liquid crystal display WEBER GEORG (DE) 2005-09-08 US disclosed
US-6905740-B2 The invention relates to a matrix liquid crystal display containing integrated non-linear elements and a liquid crystal mixture which has a particularly high resistivity. MERCK PATENT GMBH (DE) 2005-06-14 US disclosed
US-20030207046-A1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-11-06 US disclosed
US-6562419-B1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-05-13 US disclosed
US-6004479-A FLUOROETHERS FOR LIQUID CRYSTAL DISPLAYS AND DIELECTRICS MERCK KGAA (DE) 1999-12-21 US disclosed
US-5519525-A CONTAINING INTEGRATED NON-LINEAR ELEMENTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1996-05-21 US disclosed
US-5378395-A Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-01-03 US disclosed
EP-0394419-B1 MATRIX LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1994-09-21 EP disclosed
EP-0365962-B1 Matrix-type liquid-crystal display MERCK PATENT GMBH (DE) 1994-09-21 EP disclosed
US-5122295-A Containing liquid crystal mixture with high resistivity MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-06-16 US disclosed
EP-0394419-A1 MATRIX LIQUID CRYSTAL DISPLAY. MERCK PATENT GMBH (DE) 1990-10-31 EP disclosed
WO-1990004623-A1 MATRIX LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-05-03 WO disclosed
EP-0365962-A1 Matrix-type liquid-crystal display MERCK PATENT GmbH (DE) 1990-05-02 EP disclosed