Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9180980 | 0.91 | SLC6A3 (0.40) | OPRM1SLC6A9SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL4802440 | 0.89 | CYP1A2 (0.40) | OPRM1SLC6A9SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL4802446 | 0.89 | CYP1A2 (0.40) | OPRM1SLC6A9SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9177824 | 0.86 | SLC6A3 (0.42) | OPRM1SLC6A3SLC6A4SLC6A2OPRL1 | |
| SCHEMBL9574561 | 0.86 | OPRL1 (0.33) | OPRM1SLC6A9SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9574554 | 0.86 | OPRL1 (0.33) | OPRM1SLC6A9SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9177828 | 0.86 | SLC6A3 (0.42) | OPRM1SLC6A3SLC6A4SLC6A2OPRL1 | |
| SCHEMBL6524970 | 0.85 | SLC6A4 (0.51) | OPRM1SLC6A9SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9183435 | 0.83 | SLC6A4 (0.46) | SLC6A9SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10612749 | 0.82 | OPRD1 (0.36) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |