Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 7/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 7/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 7/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.53 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598459 | 0.83 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL991748 | 0.74 | PKM (0.52) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Amantadine SCHEMBL3642447 | 0.69 | GRIN1 (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Amantadine SCHEMBL21309814 | 0.69 | GRIN1 (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Amantadine SCHEMBL20409394 | 0.69 | GRIN1 (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Amantadine SCHEMBL4098 | 0.69 | GRIN1 (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Amantadine SCHEMBL15532073 | 0.69 | GRIN1 (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Amantadine SCHEMBL21310017 | 0.69 | GRIN1 (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Amantadine SCHEMBL15672299 | 0.69 | GRIN1 (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL963771 | 0.67 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347597-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-04-10 | — | — | EP | claimed |
| CN-114269798-B | High propylene content EP with low glass transition temperature | 埃克森美孚化学专利公司 | 2024-02-27 | — | — | CN | claimed |
| WO-2024015637-A1 | GLUTATHIONE PEROXIDASE 4 (GPX4) INHIBITORS FOR THE TREATMENT OF CANCER | Ferro Therapeutics, Inc. (US) | 2024-01-18 | — | — | WO | claimed |
| CN-117377674-A | Pyrazolo [1,5-a ] pyrimidine compounds for the treatment of dermatological disorders | 大塚制药株式会社 | 2024-01-09 | — | — | CN | claimed |
| CN-117298108-A | Androgen receptor and glucocorticoid receptor dual-target inhibitor and application thereof | 浙江师范大学 | 2023-12-29 | — | — | CN | claimed |
| CN-112654620-B | Novel pyrazolopyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-116410121-A | Preparation method of chiral polycyclic 3, 4-dihydro-2H-pyrrole derivative | 华中师范大学 | 2023-07-11 | — | — | CN | claimed |
| CN-116209683-A | Method for delivering non-aromatic solutions to a polymerization reactor | 埃克森美孚化学专利公司 | 2023-06-02 | — | — | CN | claimed |
| CN-112004841-B | Process for preparing high propylene content PEDM with low glass transition temperature using tetrahydroindacene based catalyst system | 埃克森美孚化学专利公司 | 2023-05-26 | — | — | CN | claimed |
| CN-111356704-B | Toluene-free silica supported single site metallocene catalyst with in situ formation of supported MAO in aliphatic solvent | 埃克森美孚化学专利公司 | 2023-05-05 | — | — | CN | claimed |
| EP-0269299-A2 | Atrial peptides | NOVO NORDISK A/S (DK) | 1988-06-01 | — | — | EP | claimed |
| WO-1988003537-A1 | NOVEL PEPTIDES | NOVO INDUSTRI A/S (DK) | 1988-05-19 | — | — | WO | claimed |
| EP-0236874-A2 | Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes | BAYER AG (DE) | 1987-09-16 | — | — | EP | claimed |
| US-4556656-A | HYPOTENSIVE, ANTIPSYCHOTIC, DIABETIC, AND ANALGESIC AGENTS | THE UPJOHN COMPANY (US) | 1985-12-03 | — | — | US | claimed |
| US-4486430-A | MELAMINE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1984-12-04 | — | — | US | claimed |
| US-4457931-A | ANTISPASMODIC | SELVI & C. S.P.A. (IT) | 1984-07-03 | — | — | US | claimed |
| EP-0005586-B1 | 2,4,6-TRIS-(SUBSTITUTED-AMINO)-S-TRIAZINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1982-04-28 | — | — | EP | claimed |
| US-4261892-A | ANTIINFLAMMATORY, ANTIARTHRITIC | AMERICAN CYANAMID COMPANY (US) | 1981-04-14 | — | — | US | claimed |
| EP-0005586-A1 | 2,4,6-Tris-(substituted-amino)-S-triazines, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-11-28 | — | — | EP | claimed |
| US-3941885-A | N-ADAMANTANYL AMINO ALKANOIC ACID | SCHERING CORPORATION (US) | 1976-03-02 | — | — | US | claimed |