SCHEMBL4802898

SCHEMBL4802898

CN(CCc1ccc(N)cc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.48
MAOB P27338 4/20 0.47
MAOA P21397 2/20 0.47
SIGMAR1 Q99720 1/20 0.45
HRH3 Q9Y5N1 2/20 0.43
KMT2A Q03164 1/20 0.43
LTB4R Q15722 1/20 0.43
LTB4R2 Q9NPC1 1/20 0.43
MCHR1 Q99705 1/20 0.43
AOC3 Q16853 1/20 0.42
MLYCD O95822 1/20 0.42
ESRRG P62508 1/20 0.42
MAPT P10636 1/20 0.42
PHLPP2 Q6ZVD8 1/20 0.41
NPY5R Q15761 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8758089 0.85 ESRRG (0.56) HRH3KMT2ALTB4RLTB4R2MCHR1
SCHEMBL1936138 0.85 LTB4R (0.43) HRH3KMT2ALTB4RLTB4R2MCHR1
SCHEMBL1520363 0.84 KMT2A (0.59) KMT2ALTB4RLTB4R2AOC3MLYCD
SCHEMBL4806015 0.84 RAB9A (0.50) KMT2AMAPT
SCHEMBL6961676 0.81 MLYCD (0.47) GFERMAOBMAOASIGMAR1HRH3
SCHEMBL1935603 0.80 LTB4R (0.42) HRH3KMT2ALTB4RLTB4R2MCHR1
SCHEMBL4487134 0.79 CYP1A2 (0.53) KMT2AMLYCDNPY5R
SCHEMBL1845384 0.79 MEN1 (0.46) GFERMAOBMAOASIGMAR1KMT2A
SCHEMBL4873059 0.79 ESRRG (0.42) GFERSIGMAR1HRH3LTB4RLTB4R2
SCHEMBL25184695 0.78 ESRRG (0.42) SIGMAR1LTB4RLTB4R2MLYCDESRRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023168291-A1 COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2023-09-07 WO disclosed
US-20230256106-A1 DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF COVAL BIOPHARMA (SHANGHAI) CO., LTD. (CN) 2023-08-17 US disclosed
EP-4225745-A1 ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME Athenex, Inc. (US) 2023-08-16 EP disclosed
WO-2008004117-A1 SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS PFIZER PRODUCTS INC. (US) 2008-01-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230256106-A1 DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF TIE1, TEK, KDR GFER 4019/4885MAOB 1949/4885MAOA 2737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.