SCHEMBL4803083

SCHEMBL4803083

Cl[Zr](Cl)C(CC1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.41
HTR2A P28223 1/20 0.32
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6856381 0.80 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL1539652 0.76 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL9226165 0.76 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL31124932 0.76 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL4447745 0.76 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL7208330 0.76 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL6912962 0.76 HTR6 (0.44) HTR6HTR2ASIGMAR1
SCHEMBL6911689 0.76 HTR6 (0.41) HTR6HTR2ASIGMAR1
SCHEMBL9846103 0.75 HTR6 (0.38) HTR6
SCHEMBL7204965 0.75 HTR6 (0.43) HTR6HTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020115801-A1 Process for preparing and using meso/racemic-[bis (indenyl) ethane] zirconium dichloride compounds RAZAVI ABBAS (BE) 2002-08-22 US claimed
US-6103656-A Process for preparing and using meso/racemic-[bis (indenyl) ethane]zirconium dichloride compounds FINA RESEARCH, S.A. (BE) 2000-08-15 US claimed
EP-0835886-A1 Process for preparing and using meso/racemic-(bis(indenyl)ethane)zirconium dichloride compounds FINA RESEARCH S.A. (BE) 1998-04-15 EP claimed
EP-0798315-B1 Process for preparing highly active, stable metallocene catalyst systems, and catalyst compositions prepared according therewith WITCO GMBH (DE) 1997-10-29 EP claimed
JP-10130322-A None JP disclosed
US-11919980-B2 Dual catalyst composition TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2024-03-05 US disclosed
EP-3661983-B1 DUAL CATALYST COMPOSITION TOTAL RES & TECHNOLOGY FELUY (BE) 2022-01-19 EP disclosed
EP-3661982-B1 DUAL CATALYST COMPOSITION TOTAL RES & TECHNOLOGY FELUY (BE) 2021-12-01 EP disclosed
US-20210155724-A1 Dual Catalyst Composition TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2021-05-27 US disclosed
US-20210087311-A1 Dual Catalyst Composition TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2021-03-25 US disclosed
EP-3661982-A1 DUAL CATALYST COMPOSITION Total Research & Technology Feluy (BE) 2020-06-10 EP disclosed
EP-3661983-A1 DUAL CATALYST COMPOSITION Total Research & Technology Feluy (BE) 2020-06-10 EP disclosed
EP-0835886-A1 Process for preparing and using meso/racemic-(bis(indenyl)ethane)zirconium dichloride compounds FINA RESEARCH S.A. (BE) 1998-04-15 EP disclosed
EP-0835886-A1 Process for preparing and using meso/racemic-(bis(indenyl)ethane)zirconium dichloride compounds FINA RESEARCH S.A. (BE) 1998-04-15 EP disclosed
WO-1997025336-A1 PREPARATION OF BISCYCLOPENTADIENYL DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-07-17 WO disclosed
EP-0775148-A1 BISCYCLOPENTADIENYL DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-05-28 EP disclosed
WO-1997014727-A1 HOMOGENEOUS METALLOCENE-BASED OLEFIN POLYMERIZATION SYSTEM WITH INCREASED ACTIVITY AMOCO CORPORATION (US) 1997-04-24 WO disclosed
US-5616664-A Polymerization process with biscyclopentadienyl diene complex containing catalysts THE DOW CHEMICAL COMPANY (US) 1997-04-01 US disclosed
US-5527929-A Zwitterionic biscyclopentadienyl complexes THE DOW CHEMICAL COMPANY (US) 1996-06-18 US disclosed
WO-1996004290-A1 BISCYCLOPENTADIENYL DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1996-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11919980-B2 Dual catalyst composition INF2, DUOX2, CPNE4 HTR6 4399/4885HTR2A 2321/4885SIGMAR1 3869/4885
US-20210087311-A1 Dual Catalyst Composition INF2, DUOX2, CPNE4 HTR6 4399/4885HTR2A 2321/4885SIGMAR1 3869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.