Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14147078 | 0.87 | GFER (0.64) | GFERALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL14147079 | 0.87 | GFER (0.50) | GFERALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL4739010 | 0.78 | RAB9A (0.58) | GFERALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL4785248 | 0.77 | GFER (1.00) | GFERALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL14147077 | 0.75 | GFER (0.51) | GFERALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL4741229 | 0.73 | MMP13 (0.58) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14147190 | 0.69 | ALDH1A1 (0.65) | GFERALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL4785714 | 0.67 | RAB9A (0.54) | GFERALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL4737012 | 0.65 | GAA (0.58) | GFERALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL22804219 | 0.63 | RAB9A (0.70) | GFERALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |