Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471489 | 1.00 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MITFMAPTHTT | |
| SCHEMBL5804020 | 0.87 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2MITFMAPTHTT | |
| SCHEMBL10347993 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MITFMAPTHTT | |
| SCHEMBL11436808 | 0.71 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2MITFMAPTHTT | |
| SCHEMBL10566648 | 0.71 | MEN1 (0.55) | ALDH1A1SMN1; SMN2MITFMAPTHTT | |
| SCHEMBL28730242 | 0.71 | HTT (0.67) | ALDH1A1SMN1; SMN2MITFMAPTHTT | |
| SCHEMBL10580020 | 0.70 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2MITFMAPTHTT | |
| SCHEMBL27993294 | 0.69 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2MITFMAPTMEN1 | |
| SCHEMBL10347982 | 0.68 | GAA (0.49) | ALDH1A1SMN1; SMN2MITFMAPTHTT | |
| SCHEMBL28727361 | 0.65 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2MITFMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | US | claimed |
| US-7420062-B2 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE, AG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | DDT, CYP1A2, HPD | ALDH1A1 769/4885SMN1; SMN2 4638/4885MITF 3887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.