Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27920240 | 0.79 | MAPT (0.62) | SMN1; SMN2MAPK1GPR35KDM4EMEN1 | |
| SCHEMBL27993082 | 0.78 | CASP1 (0.47) | SMN1; SMN2ALDH1A1KDM4ETSHRNPC1 | |
| SCHEMBL17255708 | 0.75 | LMNA (0.50) | SMN1; SMN2MAPK1ALDH1A1KDM4ETSHR | |
| SCHEMBL15442859 | 0.74 | MYC (0.55) | SMN1; SMN2ALDH1A1KDM4ETDP1NPC1 | |
| SCHEMBL10347993 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2MAPK1GPR35ALDH1A1KDM4E | |
| SCHEMBL368384 | 0.72 | GPR35 (0.44) | SMN1; SMN2MAPK1GPR35ALDH1A1TSHR | |
| SCHEMBL61902 | 0.71 | ALDH1A1 (0.67) | SMN1; SMN2MAPK1GPR35ALDH1A1KDM4E | |
| SCHEMBL16761057 | 0.71 | CA12 (0.50) | SMN1; SMN2ALDH1A1KDM4ETDP1NPC1 | |
| SCHEMBL17255678 | 0.71 | KDM4E (0.47) | ALDH1A1KDM4ETSHRTDP1MAPT | |
| SCHEMBL28102000 | 0.71 | HSD17B10 (0.51) | SMN1; SMN2ALDH1A1KDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104661661-A | External liquid preparation for resisting trichophytosis | MEIJI SEIKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |