Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854826 | 0.87 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL4063572 | 0.83 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL4749360 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL4064270 | 0.79 | HSD17B10 (0.51) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL4067973 | 0.78 | KDM4E (0.53) | ALDH1A1KDM4EHPGDHSD17B10PIK3CA | |
| SCHEMBL4817000 | 0.75 | ME2 (0.44) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL4074550 | 0.73 | KDM4E (0.62) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL4063851 | 0.73 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL4749923 | 0.71 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL4248277 | 0.70 | HSD17B10 (0.45) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |