Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749923 | 0.91 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL4746294 | 0.90 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL4749965 | 0.90 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL4749356 | 0.88 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10PRKDC | |
| SCHEMBL4787866 | 0.87 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4063572 | 0.83 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL4747065 | 0.83 | LIPE (0.40) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL4067973 | 0.81 | KDM4E (0.53) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL4804100 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL4746748 | 0.78 | L3MBTL1 (0.44) | ALDH1A1KDM4EHSD17B10MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |