Styrene

Styrene

SCHEMBL480425

C=Cc1ccccc1.CC(C)Cc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 2/20 0.41
LMNA P02545 2/20 0.41
HPGD P15428 2/20 0.41
KMT2A Q03164 2/20 0.41
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
FOLH1 Q04609 4/20 0.39
TSHR P16473 1/20 0.38
CLCN2 P51788 1/20 0.37
PTGS2 P35354 1/20 0.36
ALOX5AP P20292 1/20 0.36
DHODH Q02127 1/20 0.36
GFER P55789 1/20 0.36
ADRB3 P13945 2/20 0.35
ADRB1 P08588 1/20 0.35
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901261 0.87 GABRA1 (0.50) ALDH1A1MEN1LMNAHPGDKMT2A
SCHEMBL3671508 0.84 GABRA1 (0.47) ALDH1A1MEN1LMNAHPGDKMT2A
SCHEMBL17961587 0.79 FOLH1 (0.43) ALDH1A1MEN1LMNAHPGDKMT2A
SCHEMBL3677526 0.79 GABRA1 (0.42) ALDH1A1MEN1LMNAHPGDKMT2A
SCHEMBL690261 0.77 PRKCG (0.36) ALDH1A1MEN1LMNAHPGDKMT2A
SCHEMBL8146758 0.77 GABRA1 (0.57) ALDH1A1MEN1LMNAHPGDKMT2A
Trimethylammonium SCHEMBL28124204 0.77 FOLH1 (0.41) ALDH1A1MEN1LMNAHPGDKMT2A
Phthalic Acid SCHEMBL10549316 0.76 ALDH1A1 (0.48) ALDH1A1LMNAKMT2AFOLH1TSHR
SCHEMBL28357890 0.76 TSHR (0.49) LMNAFOLH1TSHR
SCHEMBL6558527 0.76 FOLH1 (0.45) ALDH1A1KMT2AFOLH1TSHRCLCN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1274983-B1 COLORIMETRIC ARTIFICIAL NOSE HAVING AN ARRAY OF DYES AND METHOD FOR ARTIFICIAL OLFACTION UNIV ILLINOIS (US) 2012-02-01 EP disclosed
EP-1274983-A4 COLORIMETRIC ARTIFICIAL NOSE HAVING AN ARRAY OF DYES AND METHOD FOR ARTIFICIAL OLFACTION UNIV ILLINOIS (US) 2004-12-22 EP disclosed
EP-1274983-A1 COLORIMETRIC ARTIFICIAL NOSE HAVING AN ARRAY OF DYES AND METHOD FOR ARTIFICIAL OLFACTION The Board of Trustees of the University of Illinois (US) 2003-01-15 EP disclosed
WO-2001071318-A1 COLORIMETRIC ARTIFICIAL NOSE HAVING AN ARRAY OF DYES AND METHOD FOR ARTIFICIAL OLFACTION THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2001-09-27 WO disclosed