Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.68 |
| ▸ | PPARG | P37231 | 5/20 | 0.64 |
| ▸ | PPARD | Q03181 | 5/20 | 0.64 |
| ▸ | PPARA | Q07869 | 5/20 | 0.64 |
| ▸ | F7 | P08709 | 5/20 | 0.64 |
| ▸ | F3 | P13726 | 5/20 | 0.64 |
| ▸ | TERT | O14746 | 3/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | FABP4 | P15090 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.64 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.64 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4804336 | 1.00 | ALOX5 (0.68) | ALOX5PPARGPPARDPPARAF7 | |
| SCHEMBL3318881 | 0.91 | ALOX5 (0.76) | ALOX5PPARGPPARDPPARAF7 | |
| SCHEMBL3318879 | 0.91 | ALOX5 (0.76) | ALOX5PPARGPPARDPPARAF7 | |
| SCHEMBL21173235 | 0.89 | ALOX5 (0.51) | ALOX5PPARGPPARDPPARAF7 | |
| SCHEMBL24701559 | 0.88 | CNR1 (0.64) | ALOX5MAPTBLMTDP1FAAH | |
| SCHEMBL3317425 | 0.87 | ALOX5 (0.73) | ALOX5PPARGPPARDPPARAF7 | |
| SCHEMBL3317420 | 0.87 | ALOX5 (0.73) | ALOX5PPARGPPARDPPARAF7 | |
| SCHEMBL4812943 | 0.85 | EPHX2 (0.54) | ALOX5HSD17B10MAPTBLMLMNA | |
| SCHEMBL4812926 | 0.85 | EPHX2 (0.54) | ALOX5HSD17B10MAPTBLMLMNA | |
| SCHEMBL8922724 | 0.85 | ALOX5 (0.93) | ALOX5PPARGPPARDPPARAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7468389-B2 | Carboxylic acid compound having cyclopropane ring | TOX K.K. (JP) | 2008-12-23 | — | — | US | disclosed |
| EP-1343746-B1 | USE OF CARBOXYLIC ACID COMPOUND HAVING CYCLOPROPANE RING AS MEDICAMENT | TOX KK (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-20050075393-A1 | Carboxylic acid compound cyclopropane ring | NISHIZAKI BIOINFORMATION RESEARCH INSTITUTE (JP) | 2005-04-07 | — | — | US | disclosed |
| EP-1343746-A1 | CARBOXYLIC ACID COMPOUND HAVING CYCLOPROPANE RING | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002050013-A1 | CARBOXYLIC ACID COMPOUND HAVING CYCLOPROPANE RING | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075393-A1 | Carboxylic acid compound cyclopropane ring | SLC1A2, GRIN1, BDNF | ALOX5 287/4885PPARG 1325/4885PPARD 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.