Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4812943 | 1.00 | EPHX2 (0.54) | EPHX2ALOX5CNR2CNR1TRPV1 | |
| SCHEMBL2505318 | 0.86 | ALOX5 (0.62) | EPHX2ALOX5CNR2CNR1TRPV1 | |
| SCHEMBL31039608 | 0.86 | ALOX5 (0.62) | EPHX2ALOX5CNR2CNR1TRPV1 | |
| SCHEMBL2508700 | 0.86 | ALOX5 (0.62) | EPHX2ALOX5CNR2CNR1TRPV1 | |
| SCHEMBL2508699 | 0.86 | ALOX5 (0.62) | EPHX2ALOX5CNR2CNR1TRPV1 | |
| SCHEMBL10085305 | 0.86 | ALOX5 (0.62) | EPHX2ALOX5CNR2CNR1TRPV1 | |
| SCHEMBL2505317 | 0.86 | ALOX5 (0.62) | EPHX2ALOX5CNR2CNR1TRPV1 | |
| SCHEMBL16174233 | 0.86 | ALOX5 (0.62) | EPHX2ALOX5CNR2CNR1TRPV1 | |
| SCHEMBL4804331 | 0.85 | ALOX5 (0.68) | ALOX5KDM4EALDH1A1TDP1OXER1 | |
| SCHEMBL21173235 | 0.85 | ALOX5 (0.51) | ALOX5CNR2CNR1TRPV1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7468389-B2 | Carboxylic acid compound having cyclopropane ring | TOX K.K. (JP) | 2008-12-23 | — | — | US | disclosed |
| EP-1343746-B1 | USE OF CARBOXYLIC ACID COMPOUND HAVING CYCLOPROPANE RING AS MEDICAMENT | TOX KK (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-20050075393-A1 | Carboxylic acid compound cyclopropane ring | NISHIZAKI BIOINFORMATION RESEARCH INSTITUTE (JP) | 2005-04-07 | — | — | US | disclosed |
| EP-1343746-A1 | CARBOXYLIC ACID COMPOUND HAVING CYCLOPROPANE RING | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002050013-A1 | CARBOXYLIC ACID COMPOUND HAVING CYCLOPROPANE RING | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075393-A1 | Carboxylic acid compound cyclopropane ring | SLC1A2, GRIN1, BDNF | EPHX2 997/4885ALOX5 287/4885CNR2 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.