Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 20/20 | 0.70 |
| ▸ | NOS3 | P29474 | 19/20 | 0.63 |
| ▸ | NOS2 | P35228 | 6/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122037 | 0.82 | NOS1 (1.00) | NOS1NOS3NOS2SLC6A2 | |
| SCHEMBL1121963 | 0.77 | NOS1 (1.00) | NOS1NOS3NOS2SLC6A2 | |
| SCHEMBL1122163 | 0.76 | NOS1 (0.67) | NOS1NOS3NOS2SLC6A2 | |
| SCHEMBL4562862 | 0.76 | NOS1 (0.88) | NOS1NOS3NOS2SLC6A2 | |
| SCHEMBL1122321 | 0.75 | NOS1 (1.00) | NOS1NOS3NOS2SLC6A2 | |
| SCHEMBL2265547 | 0.75 | NOS1 (0.98) | NOS1NOS3NOS2SLC6A2 | |
| Hydrochloric Acid SCHEMBL2926470 | 0.75 | NOS1 (0.78) | NOS1NOS3NOS2SLC6A2 | |
| SCHEMBL2940255 | 0.75 | NOS1 (0.78) | NOS1NOS3NOS2SLC6A2 | |
| SCHEMBL1122040 | 0.75 | NOS1 (1.00) | NOS1NOS3NOS2SLC6A2 | |
| SCHEMBL1122008 | 0.74 | NOS1 (1.00) | NOS1NOS3NOS2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375219-B2 | Substituted indole compounds having NOS inhibitory activity | NEURAXON, INC. (CA) | 2008-05-20 | — | — | US | disclosed |
| US-20060258721-A1 | Substituted indole compounds having NOS inhibitory activity | NEURAXON INC. (CA) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258721-A1 | Substituted indole compounds having NOS inhibitory activity | NOS2, NOS1, NOS3 | NOS1 2/4885NOS3 3/4885NOS2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.