Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | P4HB | P07237 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3020291 | 0.81 | CTSL (0.59) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL3020294 | 0.81 | CTSL (0.59) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL9016089 | 0.81 | CTSL (0.59) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL8651829 | 0.81 | CTSL (0.58) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL2193454 | 0.81 | CTSL (0.55) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL8650748 | 0.80 | CTSL (0.57) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL9270557 | 0.78 | CTSL (0.55) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL8650822 | 0.77 | CTSL (0.62) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL19100705 | 0.77 | CTSL (0.58) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL24178475 | 0.76 | CTSL (0.67) | TACR1CTSLCTSSCTSKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071453-A1 | 1,2-DIARYLACETYLENE DERIVATIVES OF ACYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-06-19 | — | — | WO | disclosed |