Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL4808298 | 1.00 | TP53 (0.39) | TP53CA5ACA5BTSHRTDP1 | |
| SCHEMBL4662106 | 0.92 | TSHR (0.33) | TP53TSHRTDP1 | |
| Sulfuric Acid SCHEMBL21809043 | 0.87 | THRB (0.43) | TP53CA5ACA5BTSHR | |
| SCHEMBL3885660 | 0.84 | TSHR (0.47) | TSHR | |
| SCHEMBL428320 | 0.84 | TSHR (0.47) | TSHR | |
| SCHEMBL619867 | 0.84 | TSHR (0.47) | TSHR | |
| SCHEMBL29093054 | 0.84 | TSHR (0.47) | TSHR | |
| SCHEMBL29093233 | 0.84 | TSHR (0.47) | TSHR | |
| 3-Octanol SCHEMBL8014322 | 0.83 | TP53 (0.57) | TP53 | |
| SCHEMBL12164299 | 0.81 | PTGS1 (0.36) | TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375241-B2 | Ferrocenyl-1,2-diphosphines, the production thereof and their use | SOLVIAS A.G. (CH) | 2008-05-20 | — | — | US | disclosed |
| EP-1692151-B1 | FERROCENYL-1, 2-DIPHOSPHINES, THE PRODUCTION THEREOF AND THEIR USE | SOLVIAS AG (CH) | 2007-09-12 | — | — | EP | disclosed |
| US-20070142655-A1 | Ferrocenyl-1,2-diphosphines, the production thereof and their use | SOLVIAS AG (CH) | 2007-06-21 | — | — | US | disclosed |
| EP-1692151-A1 | FERROCENYL-1, 2-DIPHOSPHINES, THE PRODUCTION THEREOF AND THEIR USE | Solvias AG (CH) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056568-A1 | FERROCENYL-1, 2-DIPHOSPHINES, THE PRODUCTION THEREOF AND THEIR USE | SOLVIAS AG (CH) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142655-A1 | Ferrocenyl-1,2-diphosphines, the production thereof and their use | PHOSPHO1, INPP5B, PPA1 | TP53 3856/4885CA5A 193/4885CA5B 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.