SCHEMBL480740

SCHEMBL480740

CC(=CCc1ccc(-c2ccccc2)cc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
ABCC4 O15439 1/20 0.48
GAA P10253 1/20 0.48
TSHR P16473 1/20 0.48
PTGS1 P23219 1/20 0.48
HTT P42858 1/20 0.48
FFAR1 O14842 1/20 0.46
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
AKR1C3 P42330 1/20 0.44
CYP2C9 P11712 1/20 0.42
PTPN1 P18031 1/20 0.42
GSK3B P49841 1/20 0.42
TP53 P04637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MMP12 P39900 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17940828 1.00 LMNA (0.48) LMNAABCC4GAATSHRPTGS1
Biphenyl SCHEMBL28243732 0.95 CYP2C9 (0.47) LMNAABCC4GAATSHRPTGS1
SCHEMBL30530 0.89 CYP2C9 (0.51) LMNAPTGS1HTTMAPTSMN1; SMN2
SCHEMBL30528 0.89 CYP2C9 (0.51) LMNAPTGS1HTTMAPTSMN1; SMN2
Iodide SCHEMBL3761279 0.87 CYP2C9 (0.50) LMNAPTGS1HTTMAPTSMN1; SMN2
SCHEMBL19097596 0.86 LMNA (0.55) LMNAAKR1C3CYP2C9KMT2AALDH1A1
SCHEMBL19097595 0.86 LMNA (0.55) LMNAAKR1C3CYP2C9KMT2AALDH1A1
SCHEMBL15733040 0.85 PTGS2 (0.48) AKR1C3CYP2C9
SCHEMBL6736212 0.84 CYP2C9 (0.47) LMNAHTTMAPTSMN1; SMN2AKR1C3
SCHEMBL6736205 0.84 CYP2C9 (0.47) LMNAHTTMAPTSMN1; SMN2AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9156931-B2 Radical polymerizable composition, cured product, and plastic lens DIC CORPORATION (JP) 2015-10-13 US claimed
US-20140148525-A1 RADICAL POLYMERIZABLE COMPOSITION, CURED PRODUCT, AND PLASTIC LENS DIC CORPORATION (JP) 2014-05-29 US claimed
EP-3413102-B1 LIGHT DIFFUSING AGENT, LIGHT DIFFUSING RESIN COMPOSITION AND MOLDED BODY MITSUBISHI GAS CHEMICAL CO (JP) 2022-04-06 EP disclosed
US-10920000-B2 Light diffusing agent, light diffusing resin composition and molded body MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-02-16 US disclosed
US-10731033-B2 (Meth)acrylic copolymer, resin composition, and molded product of said resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-08-04 US disclosed
EP-3255101-B1 POLYCARBONATE RESIN COMPOSITION AND ARTICLE MOLDED THEREFROM MITSUBISHI GAS CHEMICAL CO (JP) 2019-05-01 EP disclosed
US-20190031799-A1 LIGHT DIFFUSING AGENT, LIGHT DIFFUSING RESIN COMPOSITION AND MOLDED BODY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2019-01-31 US disclosed
US-20180362759-A1 (METH)ACRYLIC COPOLYMER, RESIN COMPOSITION, AND MOLDED PRODUCT OF SAID RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-12-20 US disclosed
EP-3413102-A1 LIGHT DIFFUSING AGENT, LIGHT DIFFUSING RESIN COMPOSITION AND MOLDED BODY Mitsubishi Gas Chemical Company, Inc. (JP) 2018-12-12 EP disclosed
EP-3056542-B1 (METH)ACRYLIC COPOLYMER, RESIN COMPOSITION, AND MOLDED PRODUCT OF SAID RESIN COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2018-11-28 EP disclosed
US-10138372-B2 Polycarbonate resin composition and article molded therefrom MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-11-27 US disclosed
EP-3056542-A1 (METH)ACRYLIC COPOLYMER, RESIN COMPOSITION, AND MOLDED PRODUCT OF SAID RESIN COMPOSITION Mitsubishi Gas Chemical Company, Inc. (JP) 2016-08-17 EP disclosed
US-20160215139-A1 (METH)ACRYLIC COPOLYMER, RESIN COMPOSITION, AND MOLDED PRODUCT OF SAID RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-07-28 US disclosed
US-9156931-B2 Radical polymerizable composition, cured product, and plastic lens DIC CORPORATION (JP) 2015-10-13 US disclosed
US-20140148525-A1 RADICAL POLYMERIZABLE COMPOSITION, CURED PRODUCT, AND PLASTIC LENS DIC CORPORATION (JP) 2014-05-29 US disclosed
US-8183313-B2 Light guide including surface-treated resin OMRON CORPORATION (JP) 2012-05-22 US disclosed
EP-2082872-B1 LIGHT GUIDE HAVING A SURFACE-TREATED RESIN, AND PRODUCTION METHOD THEREOF OMRON TATEISI ELECTRONICS CO (JP) 2012-02-01 EP disclosed
US-20100304153-A1 SURFACE-TREATED RESIN, METHOD FOR PRODUCING THE SAME, AND USE OF THE SAME OMRON CORPORATION (JP) 2010-12-02 US disclosed
EP-2082872-A1 SURFACE-TREATED RESIN, METHOD FOR PRODUCING THE SAME, AND USE OF THE SAME OMRON Corporation, a corporation of Japan (JP) 2009-07-29 EP disclosed
US-20070172772-A1 Microlens OMRON CORPORATION (JP) 2007-07-26 US disclosed