Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744284 | 0.85 | KMT2A (0.47) | ADAMTS5KMT2AMAPK1MAOBALDH1A1 | |
| SCHEMBL4810958 | 0.72 | KIF11 (0.43) | ADAMTS5ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL633139 | 0.72 | MAOB (0.70) | ATMKMT2AMAOBALDH1A1MAOA | |
| SCHEMBL30307025 | 0.72 | MAOB (0.70) | ATMKMT2AMAOBALDH1A1MAOA | |
| SCHEMBL4848527 | 0.70 | NR1H2 (0.35) | ADAMTS5ALDH1A1GAALTA4HPPARG | |
| SCHEMBL6686421 | 0.65 | GFER (0.47) | ADAMTS5MAOBALDH1A1MAOAGAA | |
| SCHEMBL29352463 | 0.63 | MAOB (0.86) | ATMKMT2AMAOBALDH1A1MAOA | |
| SCHEMBL128748 | 0.63 | MAOB (0.86) | ATMKMT2AMAOBALDH1A1MAOA | |
| SCHEMBL204267 | 0.63 | MAOB (0.86) | ATMKMT2AMAOBALDH1A1MAOA | |
| SCHEMBL29363390 | 0.63 | MAOB (0.86) | ATMKMT2AMAOBALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |