SCHEMBL4808835

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4816034	0.89	THRB (0.47)	THRATHRBNR3C1PGRMEN1
	SCHEMBL4810919	0.89	THRA (0.50)	THRATHRBESR1NR3C1PGR
	SCHEMBL4818644	0.86	THRA (0.48)	THRATHRBSLC1A5ESR1NR3C1
	SCHEMBL4808246	0.84	THRA (0.46)	THRATHRBSLC1A5ESR1NR3C1
	SCHEMBL4815513	0.83	SLC1A5 (0.49)	THRATHRBSLC1A5MAOBMAOA
	SCHEMBL4809557	0.83	THRA (0.45)	THRATHRBMAOBMEN1LMNA
	SCHEMBL4812326	0.82	THRA (0.64)	THRATHRBESR1NR3C1PGR
	SCHEMBL4899376	0.82	THRA (0.64)	THRATHRBESR1NR3C1PGR
	SCHEMBL4809817	0.82	THRB (0.46)	THRATHRBNR3C1PGRMAOB
	SCHEMBL4812514	0.80	SLC1A5 (0.47)	THRATHRBSLC1A5MAOBPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.