Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811562 | 0.79 | CYP2D6 (0.34) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL4812454 | 0.79 | KCNN4 (0.35) | KCNN4LMNAMAPK1ALDH1A1 | |
| SCHEMBL4808354 | 0.75 | TSHR (0.32) | KCNN4ALDH1A1 | |
| SCHEMBL4813376 | 0.73 | CYP2D6 (0.37) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL4815486 | 0.72 | KCNN4 (0.33) | KCNN4MAPK1ALDH1A1CYP2D6 | |
| SCHEMBL4814452 | 0.72 | TSHR (0.30) | KCNN4ALDH1A1 | |
| SCHEMBL4807979 | 0.71 | KCNN4 (0.39) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL6267708 | 0.71 | — | — | |
| SCHEMBL5968381 | 0.70 | CYP2D6 (0.36) | KCNN4TAAR1MAPK1ALDH1A1CYP2D6 | |
| SCHEMBL4815056 | 0.69 | KCNN4 (0.31) | KCNN4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7059382-B2 | Method of incorporating brominated compounds as additives to expanded polystyrene molded patterns for use in lost foam aluminum casting | GENERAL MOTORS CORPORATION (US) | 2006-06-13 | — | — | US | claimed |
| US-20050043464-A1 | Method of incorporating brominated compounds as additives to expanded polystyrene molded patterns for use in lost foam aluminum casting | GM Global Technology Operations LLC | 2005-02-24 | — | — | US | claimed |
| US-7405254-B2 | Brominated anionic styrenic polymer, and decabromodiphenylpropane or decabromodiphenylethane | ALBEMARLE CORPORATION (US) | 2008-07-29 | — | — | US | disclosed |
| EP-1711555-B1 | FLAME RETARDANT COMPOSITIONS AND THEIR USE | ALBEMARLE CORP (US) | 2008-07-09 | — | — | EP | disclosed |
| US-20070117904-A1 | Flame Retardant Compositions and Their Use | ALBEMARLE CORPORATION (US) | 2007-05-24 | — | — | US | disclosed |
| US-7202296-B2 | Flame retardant compositions and their use | ALBEMARLE CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |
| EP-1711555-A1 | FLAME RETARDANT COMPOSITIONS AND THEIR USE | ALBEMARLE CORPORATION (US) | 2006-10-18 | — | — | EP | disclosed |
| US-7059382-B2 | Method of incorporating brominated compounds as additives to expanded polystyrene molded patterns for use in lost foam aluminum casting | GENERAL MOTORS CORPORATION (US) | 2006-06-13 | — | — | US | disclosed |
| WO-2005063869-A1 | FLAME RETARDANT COMPOSITIONS AND THEIR USE | ALBEMARLE CORPORATION (US) | 2005-07-14 | — | — | WO | disclosed |
| US-20050137311-A1 | Flame retardant compositions and their use | ALBEMARLE CORPORATION | 2005-06-23 | — | — | US | disclosed |
| US-20050043464-A1 | Method of incorporating brominated compounds as additives to expanded polystyrene molded patterns for use in lost foam aluminum casting | GM Global Technology Operations LLC | 2005-02-24 | — | — | US | disclosed |