SCHEMBL4815486

SCHEMBL4815486

BrC(Br)C(Br)(Br)C(Br)(Br)C(Br)(Br)C(Br)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 6/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 2/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
TRPA1 O75762 1/20 0.32
CYP2D6 P10635 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4812454 0.93 KCNN4 (0.35) KCNN4TSHRALDH1A1TRPA1MAPK1
SCHEMBL4950960 0.84 KIF11 (0.40) TSHRALDH1A1CYP2D6NPSR1MAPT
SCHEMBL4815056 0.83 KCNN4 (0.31) KCNN4TSHRALDH1A1CYP1A2CES2
SCHEMBL4813376 0.83 CYP2D6 (0.37) KCNN4TSHRALDH1A1CYP1A2CES2
SCHEMBL4808354 0.76 TSHR (0.32) KCNN4TSHRALDH1A1
SCHEMBL4811562 0.76 CYP2D6 (0.34) KCNN4TSHRALDH1A1CYP1A2CYP2D6
SCHEMBL4815053 0.75 KCNN4 (0.39) KCNN4TSHRALDH1A1CYP1A2MAPK1
SCHEMBL651122 0.75 ALDH1A1 (0.43) KCNN4TSHRALDH1A1CYP1A2CES2
SCHEMBL4812223 0.73 KCNN4 (0.38) KCNN4TSHRALDH1A1CYP1A2MAPK1
SCHEMBL4814452 0.72 TSHR (0.30) KCNN4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7405254-B2 Brominated anionic styrenic polymer, and decabromodiphenylpropane or decabromodiphenylethane ALBEMARLE CORPORATION (US) 2008-07-29 US disclosed
EP-1711555-B1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORP (US) 2008-07-09 EP disclosed
US-20070117904-A1 Flame Retardant Compositions and Their Use ALBEMARLE CORPORATION (US) 2007-05-24 US disclosed
US-7202296-B2 Flame retardant compositions and their use ALBEMARLE CORPORATION (US) 2007-04-10 US disclosed
EP-1711555-A1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORPORATION (US) 2006-10-18 EP disclosed
WO-2005063869-A1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORPORATION (US) 2005-07-14 WO disclosed
US-20050137311-A1 Flame retardant compositions and their use ALBEMARLE CORPORATION 2005-06-23 US disclosed