Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811562 | 0.94 | CYP2D6 (0.34) | CYP2D6CYP1A2KCNN4MAPK1CYP2C19 | |
| SCHEMBL5968381 | 0.85 | CYP2D6 (0.36) | CYP2D6CYP1A2KCNN4MAPK1CYP2C19 | |
| SCHEMBL4815486 | 0.83 | KCNN4 (0.33) | CYP2D6CYP1A2KCNN4MAPTKMT2A | |
| SCHEMBL4815056 | 0.79 | KCNN4 (0.31) | CYP1A2KCNN4ALDH1A1TSHRCES2 | |
| SCHEMBL4812454 | 0.76 | KCNN4 (0.35) | KCNN4MAPK1ALDH1A1TSHR | |
| SCHEMBL4808935 | 0.73 | GRIN1 (0.37) | CYP2D6KCNN4MAPK1CYP2C19ALDH1A1 | |
| SCHEMBL4950960 | 0.73 | KIF11 (0.40) | CYP2D6MAPTKMT2AMAPK1CYP2C19 | |
| SCHEMBL4810680 | 0.73 | MAPK1 (0.42) | KCNN4MAPTKMT2AMAPK1CYP2C19 | |
| SCHEMBL4808354 | 0.72 | TSHR (0.32) | KCNN4ALDH1A1TSHR | |
| SCHEMBL4815053 | 0.72 | KCNN4 (0.39) | CYP1A2KCNN4MAPK1CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405254-B2 | Brominated anionic styrenic polymer, and decabromodiphenylpropane or decabromodiphenylethane | ALBEMARLE CORPORATION (US) | 2008-07-29 | — | — | US | disclosed |
| EP-1711555-B1 | FLAME RETARDANT COMPOSITIONS AND THEIR USE | ALBEMARLE CORP (US) | 2008-07-09 | — | — | EP | disclosed |
| US-20070117904-A1 | Flame Retardant Compositions and Their Use | ALBEMARLE CORPORATION (US) | 2007-05-24 | — | — | US | disclosed |
| US-7202296-B2 | Flame retardant compositions and their use | ALBEMARLE CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |
| EP-1711555-A1 | FLAME RETARDANT COMPOSITIONS AND THEIR USE | ALBEMARLE CORPORATION (US) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005063869-A1 | FLAME RETARDANT COMPOSITIONS AND THEIR USE | ALBEMARLE CORPORATION (US) | 2005-07-14 | — | — | WO | disclosed |
| US-20050137311-A1 | Flame retardant compositions and their use | ALBEMARLE CORPORATION | 2005-06-23 | — | — | US | disclosed |