Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HA1 | P13674 | 3/20 | 0.64 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.64 |
| ▸ | MIF | P14174 | 1/20 | 0.61 |
| ▸ | GABRP | O00591 | 1/20 | 0.59 |
| ▸ | GABRD | O14764 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.59 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.59 |
| ▸ | GABRE | P78334 | 1/20 | 0.59 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.59 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.59 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.59 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595340 | 0.79 | KCNJ1 (0.47) | P4HA1P4HTMMIFGABRPGABRD | |
| SCHEMBL29397057 | 0.78 | P4HTM (1.00) | P4HA1P4HTMMIFGABRPGABRD | |
| SCHEMBL29683317 | 0.78 | P4HTM (1.00) | P4HA1P4HTMMIFGABRPGABRD | |
| SCHEMBL68560 | 0.78 | P4HTM (1.00) | P4HA1P4HTMMIFGABRPGABRD | |
| Potassium SCHEMBL30900922 | 0.76 | P4HTM (0.95) | P4HA1P4HTMMIFGABRPGABRD | |
| Hydrochloric Acid SCHEMBL8871610 | 0.76 | P4HTM (0.95) | P4HA1P4HTMMIFGABRPGABRD | |
| Pyridine-2,5-Dicarboxylic Acid SCHEMBL29363410 | 0.76 | P4HTM (1.00) | P4HA1P4HTMMIFGABRPGABRD | |
| SCHEMBL185991 | 0.76 | P4HA1 (0.64) | P4HA1P4HTMMIFGABRPGABRD | |
| Pyridine-2,5-Dicarboxylic Acid SCHEMBL70231 | 0.76 | P4HTM (1.00) | P4HA1P4HTMMIFGABRPGABRD | |
| SCHEMBL29524968 | 0.76 | P4HA1 (0.64) | P4HA1P4HTMMIFGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320986-B2 | Fused tri and tetra-cyclic pyrazole kinase inhibitors | ABBOTT LABORTORIES (US) | 2008-01-22 | — | — | US | disclosed |
| EP-1603885-A1 | FUSED TRI AND TETRA-CYCLIC PYRAZOLE KINASE INHIBITORS | Abbott Laboratories (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20040259904-A1 | Fused tri and tetra-cyclic pyrazole kinase inhibitors | ABBVIE INC. | 2004-12-23 | — | — | US | disclosed |
| WO-2004080973-A1 | FUSED TRI AND TETRA-CYCLIC PYRAZOLE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259904-A1 | Fused tri and tetra-cyclic pyrazole kinase inhibitors | TK1, MAP3K19, MAP3K20 | P4HA1 2514/4885P4HTM 3577/4885MIF 2828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.