SCHEMBL4811042

SCHEMBL4811042

CCC(S)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.44
TAAR1 Q96RJ0 1/20 0.41
MAPK1 P28482 1/20 0.39
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TP53 P04637 1/20 0.38
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
ALOX15 P16050 1/20 0.36
LMNA P02545 1/20 0.35
PTPN1 P18031 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL767319 0.81 KCNN4 (0.46) KCNN4TAAR1MAPK1TSHRALDH1A1
SCHEMBL9120335 0.80 KCNN4 (0.41) KCNN4TAAR1MAPK1TSHRTP53
SCHEMBL3701035 0.79 KCNN4 (0.44) KCNN4TAAR1MAPK1TSHRALDH1A1
Hydrogen Sulfide SCHEMBL28845172 0.79 KCNN4 (0.44) KCNN4TAAR1MAPK1TSHRALDH1A1
SCHEMBL27855411 0.78 KCNN4 (0.41) KCNN4TAAR1MAPK1TSHRALDH1A1
SCHEMBL879532 0.77 TAAR1 (0.44) KCNN4TAAR1MAPK1TSHRALDH1A1
SCHEMBL12834072 0.77 TAAR1 (0.44) KCNN4TAAR1MAPK1TSHRALDH1A1
SCHEMBL14608023 0.77 TAAR1 (0.44) KCNN4TAAR1MAPK1TSHRALDH1A1
SCHEMBL6831120 0.76 KCNN4 (0.39) KCNN4TAAR1MAPK1TSHRALDH1A1
SCHEMBL5738021 0.74 KCNN4 (0.44) KCNN4TAAR1MAPK1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7358597-B2 UV-activated dielectric layer INTEL CORPORATION (US) 2008-04-15 US disclosed
US-20050156288-A1 UV-activated dielectric layer GOODNER MICHAEL D (US) 2005-07-21 US disclosed
US-6893985-B2 UV-activated dielectric layer INTEL CORPORATION (US) 2005-05-17 US disclosed
US-20040191696-A1 UV-activated dielectric layer INTEL CORPORATION 2004-09-30 US disclosed
EP-0896050-A1 Lubricating oil composition comprising a specific base oil and an oxidation inhibitor NIPPON OIL CO., LTD. (JP) 1999-02-10 EP disclosed