Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28845172

CCC(S)(CC)c1ccccc1.S

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.44
TAAR1 Q96RJ0 1/20 0.41
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
CYP2C19 P33261 2/20 0.37
HIF1A Q16665 1/20 0.37
ALOX15 P16050 1/20 0.36
ESR1 P03372 1/20 0.34
CYP3A4 P08684 1/20 0.34
ESR2 Q92731 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL767319 0.97 KCNN4 (0.46) KCNN4TAAR1MAPK1ALDH1A1TSHR
SCHEMBL14394144 0.86 KCNN4 (0.39) KCNN4TAAR1MAPK1TSHRCYP2C19
SCHEMBL11673454 0.80 KCNN4 (0.41) KCNN4TAAR1MAPK1TSHRTP53
SCHEMBL4811042 0.79 KCNN4 (0.44) KCNN4TAAR1MAPK1ALDH1A1TSHR
SCHEMBL3701035 0.79 KCNN4 (0.44) KCNN4TAAR1MAPK1ALDH1A1TSHR
SCHEMBL879532 0.77 TAAR1 (0.44) KCNN4TAAR1MAPK1ALDH1A1TSHR
SCHEMBL14608023 0.77 TAAR1 (0.44) KCNN4TAAR1MAPK1ALDH1A1TSHR
SCHEMBL12834072 0.77 TAAR1 (0.44) KCNN4TAAR1MAPK1ALDH1A1TSHR
SCHEMBL11431120 0.77 KIF11 (0.41) KCNN4TAAR1ESR1ESR2
SCHEMBL17067295 0.75 ELANE (0.53) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790414-A Coating composition for pattern reversion 日产化学株式会社 2019-05-21 CN disclosed
CN-103339569-B The composition of the formation resist lower membrane containing silicon comprising the organic group containing diketone structure 日产化学工业株式会社 2018-12-07 CN disclosed
CN-103718111-B The photoetching film-forming composition of titaniferous and silicon 日产化学工业株式会社 2017-06-23 CN disclosed