Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811130 | 1.00 | ADRB3 (0.45) | ADRB3ADRB1 | |
| SCHEMBL4818089 | 0.90 | ADRB3 (0.53) | ADRB3 | |
| SCHEMBL4818066 | 0.90 | ADRB3 (0.53) | ADRB3 | |
| SCHEMBL4816801 | 0.90 | ADRB3 (0.47) | ADRB3ADRB1 | |
| SCHEMBL4816789 | 0.90 | ADRB3 (0.47) | ADRB3ADRB1 | |
| SCHEMBL5699440 | 0.88 | KEAP1 (0.39) | ADRB3ADRB1 | |
| SCHEMBL5699447 | 0.88 | KEAP1 (0.39) | ADRB3ADRB1 | |
| SCHEMBL4816809 | 0.86 | ADRB3 (0.43) | ADRB3ADRB1 | |
| SCHEMBL4816803 | 0.86 | ADRB3 (0.43) | ADRB3ADRB1 | |
| SCHEMBL4818620 | 0.82 | ADRB3 (0.58) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417169-B2 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-26 | — | — | US | disclosed |
| EP-1679304-A1 | AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |