Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4816803 | 1.00 | ADRB3 (0.43) | ADRB3HPGDRECQLADRB2ADRB1 | |
| SCHEMBL4816801 | 0.91 | ADRB3 (0.47) | ADRB3ADRB1 | |
| SCHEMBL4816789 | 0.91 | ADRB3 (0.47) | ADRB3ADRB1 | |
| SCHEMBL4818653 | 0.88 | ADRB3 (0.44) | ADRB3HPGDRECQLADRB2ADRB1 | |
| SCHEMBL4818657 | 0.88 | ADRB3 (0.44) | ADRB3HPGDRECQLADRB2ADRB1 | |
| SCHEMBL4816805 | 0.87 | ADRB3 (0.51) | ADRB3ADRB2ADRB1 | |
| SCHEMBL4816811 | 0.87 | ADRB3 (0.51) | ADRB3ADRB2ADRB1 | |
| SCHEMBL4820449 | 0.86 | ADRB3 (0.39) | ADRB3HPGDRECQLADRB1 | |
| SCHEMBL4820454 | 0.86 | ADRB3 (0.39) | ADRB3HPGDRECQLADRB1 | |
| Hydrochloric Acid SCHEMBL4819404 | 0.86 | ADRB3 (0.51) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417169-B2 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | ADRB2, ADRA2A, ADRA1A | ADRB3 5/4885HPGD 1970/4885RECQL 3659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.