Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4815517 | 0.83 | POLB (0.42) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL7023958 | 0.81 | NPC1 (0.50) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10889026 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10845523 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11639470 | 0.79 | KDM4E (0.48) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL27846651 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL9620568 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11636558 | 0.78 | ALDH1A1 (0.66) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10564311 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL7452390 | 0.77 | MAPT (0.49) | ALDH1A1KDM4ENPC1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414011-B2 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (US) | 2008-08-19 | — | — | US | disclosed |
| EP-1153016-B1 | PHENYLSULFONYL UREAS, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2007-09-05 | — | — | EP | disclosed |
| US-7078369-B2 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2006-07-18 | — | — | US | disclosed |
| US-20060014644-A1 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH | 2006-01-19 | — | — | US | disclosed |
| US-20040176251-A1 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE GMBH (DE) | 2004-09-09 | — | — | US | disclosed |
| EP-1153016-A1 | PHENYLSULFONYL UREAS, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Aventis CropScience GmbH (DE) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000047566-A1 | PHENYLSULFONYL UREAS, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176251-A1 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | CBR1, CBR3, CYC1 | ALDH1A1 1863/4885KDM4E 392/4885NPC1 4345/4885 |
| US-20060014644-A1 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | CBR3, CBR1, CYC1 | ALDH1A1 2569/4885KDM4E 960/4885NPC1 4469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.