Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11639176 | 0.88 | THRB (0.48) | TDP1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL11045779 | 0.87 | KDM4E (0.41) | POLBTDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL4811798 | 0.83 | ALDH1A1 (0.43) | KDM4ENPC1ALDH1A1GAAMAPT | |
| SCHEMBL11149394 | 0.82 | THRB (0.45) | TDP1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL11635655 | 0.82 | THRB (0.45) | KDM4ENPC1ALDH1A1MAPTSLC10A6 | |
| SCHEMBL11042813 | 0.81 | KDM4E (0.39) | KDM4ENPC1ALDH1A1GAAMAPT | |
| SCHEMBL11153158 | 0.80 | SLC10A6 (0.42) | KDM4ENPC1ALDH1A1GAAMAPT | |
| SCHEMBL9064624 | 0.79 | MAPT (0.44) | TDP1KDM4ENPC1ALDH1A1GAA | |
| SCHEMBL10922201 | 0.79 | MAPT (0.48) | POLBTDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL7023958 | 0.78 | NPC1 (0.50) | POLBTDP1KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414011-B2 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (US) | 2008-08-19 | — | — | US | disclosed |
| EP-1153016-B1 | PHENYLSULFONYL UREAS, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2007-09-05 | — | — | EP | disclosed |
| US-7078369-B2 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2006-07-18 | — | — | US | disclosed |
| US-20060014644-A1 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH | 2006-01-19 | — | — | US | disclosed |
| US-20040176251-A1 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE GMBH (DE) | 2004-09-09 | — | — | US | disclosed |
| EP-1153016-A1 | PHENYLSULFONYL UREAS, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Aventis CropScience GmbH (DE) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000047566-A1 | PHENYLSULFONYL UREAS, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176251-A1 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | CBR1, CBR3, CYC1 | POLB 1823/4885TDP1 3931/4885KDM4E 392/4885 |
| US-20060014644-A1 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | CBR3, CBR1, CYC1 | POLB 1846/4885TDP1 4471/4885KDM4E 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.