SCHEMBL481337

SCHEMBL481337

COc1cc(I)c(OC)cc1I

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.54
HTR2C P28335 5/20 0.54
HTR2B P41595 4/20 0.54
CYP3A4 P08684 3/20 0.54
HTR1A P08908 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
TSHR P16473 1/20 0.54
NFKB1 P19838 1/20 0.54
PMP22 Q01453 2/20 0.52
LMNA P02545 1/20 0.52
MAPT P10636 3/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HRH1 P35367 1/20 0.42
OPRM1 P35372 1/20 0.42
OPRK1 P41145 1/20 0.42
HTR6 P50406 1/20 0.42
CA9 Q16790 2/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28211962 0.94 HTR2A (0.50) HTR2AHTR2CHTR2BCYP3A4HTR1A
SCHEMBL481617 0.90 HTR2A (0.47) HTR2AHTR2CHTR2BCYP3A4HTR1A
SCHEMBL481354 0.87 CYP3A4 (0.48) HTR2AHTR2CHTR2BCYP3A4HTR1A
SCHEMBL7139169 0.87 HTR2A (0.46) HTR2AHTR2CHTR2BCYP3A4HTR1A
SCHEMBL27560259 0.87 MAPT (0.50) HTR2AHTR2CHTR2BCYP3A4HTR1A
SCHEMBL5531158 0.87 HTR2A (0.46) HTR2AHTR2CHTR2BCYP3A4HTR1A
SCHEMBL16024606 0.85 PDE4A (0.44) HTR2AHTR2CHTR2BCYP3A4HTR1A
SCHEMBL13805536 0.84 POLB (0.58) HTR2AHTR2CHTR2BCYP3A4HTR1A
SCHEMBL22342696 0.84 HTR2A (0.44) HTR2AHTR2CHTR2BCYP3A4HTR1A
SCHEMBL22595830 0.84 HTR2A (0.44) HTR2AHTR2CHTR2BCYP3A4HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116375682-B Electrochromic material based on bithiophene, preparation method thereof and electrochromic film 平湖市浙江工业大学新材料研究院 2025-03-04 CN claimed
CN-116375682-A Electrochromic material based on bithiophene, preparation method thereof and electrochromic film 平湖市浙江工业大学新材料研究院 2023-07-04 CN claimed
CN-102660001-A Synthesis method of conjugated polymer gelling agent polyphenylene ethynylene and preparation method of gel of the conjugated polymer gelata polyphenylene ethynylene UNIV NANJING POSTS & TELECOMM 2012-09-12 CN claimed
CN-101831054-B Method for distinguishing fungi and bacteria CHINESE ACAD INST CHEMISTRY 2011-11-16 CN claimed
CN-101831054-A Method for distinguishing fungi and bacteria CHINESE ACAD INST CHEMISTRY 2010-09-15 CN claimed
US-12378274-B2 Solid solution approach for redox active metal organic frameworks with tunable redox conductivity UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2025-08-05 US disclosed
CN-115088892-B Cationic conjugated microporous polymer modified antibacterial and antiviral mask 陕西师范大学 2025-04-15 CN disclosed
CN-116375682-B Electrochromic material based on bithiophene, preparation method thereof and electrochromic film 平湖市浙江工业大学新材料研究院 2025-03-04 CN disclosed
US-20240287115-A1 SOLID SOLUTION APPROACH FOR REDOX ACTIVE METAL ORGANIC FRAMEWORKS WITH TUNABLE REDOX CONDUCTIVITY UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. 2024-08-29 US disclosed
US-11964992-B2 Solid solution approach for redox active metal organic frameworks with tunable redox conductivity UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2024-04-23 US disclosed
CN-117747913-A Lithium ion battery 珠海冠宇电池股份有限公司 2024-03-22 CN disclosed
CN-113912636-B Silicon-containing heterocyclic compound and organic electroluminescent element containing the same 上海八亿时空先进材料有限公司 2023-10-27 CN disclosed
EP-1837324-A1 PROCESS FOR PRODUCING AROMATIC IODINE COMPOUND Nippoh Chemicals Co., Ltd (JP) 2007-09-26 EP disclosed
US-20070049758-A1 Urogenital disorders; incotinence; analgesics; respiratory system disorders; gastrointestinal disorders; premenstrual tension ROCHE PALO ALTO LLC 2007-03-01 US disclosed
US-20070049758-A1 Urogenital disorders; incotinence; analgesics; respiratory system disorders; gastrointestinal disorders; premenstrual tension ROCHE PALO ALTO LLC 2007-03-01 US disclosed
US-20070049758-A1 Urogenital disorders; incotinence; analgesics; respiratory system disorders; gastrointestinal disorders; premenstrual tension ROCHE PALO ALTO LLC 2007-03-01 US disclosed
US-20070049609-A1 Methods of using diaminopyrimidine P2X3 and P2X2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases ROCHE PALO ALTO LLC 2007-03-01 US disclosed
US-20070049609-A1 Methods of using diaminopyrimidine P2X3 and P2X2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases ROCHE PALO ALTO LLC 2007-03-01 US disclosed
US-5243060-A Polymerization of diethynyl silane and dihaloarylene in the presence of a catalyst IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 1993-09-07 US disclosed
US-4647446-A Rapid brain scanning radiopharmaceutical THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1987-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378274-B2 Solid solution approach for redox active metal organic frameworks with tunable redox conductivity GPX4, FTO, GPX1 HTR2A 4062/4885HTR2C 4256/4885HTR2B 4841/4885
US-20070049758-A1 Urogenital disorders; incotinence; analgesics; respiratory system disorders; gastrointestinal disorders; premenstrual tension P2RX3, P2RX1, P2RX2 HTR2A 315/4885HTR2C 206/4885HTR2B 112/4885
US-20240287115-A1 SOLID SOLUTION APPROACH FOR REDOX ACTIVE METAL ORGANIC FRAMEWORKS WITH TUNABLE REDOX CONDUCTIVITY GPX4, FTO, GPX1 HTR2A 4062/4885HTR2C 4256/4885HTR2B 4841/4885
US-20070049609-A1 Methods of using diaminopyrimidine P2X3 and P2X2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases P2RX3, P2RX2, P2RX1 HTR2A 730/4885HTR2C 719/4885HTR2B 378/4885
US-11964992-B2 Solid solution approach for redox active metal organic frameworks with tunable redox conductivity GPX4, FTO, GPX1 HTR2A 4062/4885HTR2C 4256/4885HTR2B 4841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.