SCHEMBL4813380

SCHEMBL4813380

BrC(Br)C(Br)C(Br)C(Br)C(Br)(Br)C(Br)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.31
KCNN4 O15554 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4810684 0.94 TSHR (0.32) TSHRKCNN4ALDH1A1
SCHEMBL4814615 0.85 KCNN4 (0.35) TSHRKCNN4ALDH1A1
SCHEMBL4814452 0.82 TSHR (0.30) TSHRKCNN4ALDH1A1
SCHEMBL4811564 0.80 KCNN4 (0.35) TSHRKCNN4ALDH1A1
SCHEMBL4807982 0.78 KCNN4 (0.33) TSHRKCNN4ALDH1A1
SCHEMBL4808354 0.72 TSHR (0.32) TSHRKCNN4ALDH1A1
SCHEMBL5968381 0.71 CYP2D6 (0.36) TSHRKCNN4ALDH1A1
SCHEMBL4815056 0.71 KCNN4 (0.31) TSHRKCNN4ALDH1A1
SCHEMBL26697300 0.68 ALDH1A1 (0.50) TSHRKCNN4ALDH1A1
SCHEMBL5650092 0.67 KIF11 (0.39) TSHRKCNN4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7405254-B2 Brominated anionic styrenic polymer, and decabromodiphenylpropane or decabromodiphenylethane ALBEMARLE CORPORATION (US) 2008-07-29 US disclosed
EP-1711555-B1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORP (US) 2008-07-09 EP disclosed
US-20070117904-A1 Flame Retardant Compositions and Their Use ALBEMARLE CORPORATION (US) 2007-05-24 US disclosed
US-7202296-B2 Flame retardant compositions and their use ALBEMARLE CORPORATION (US) 2007-04-10 US disclosed
EP-1711555-A1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORPORATION (US) 2006-10-18 EP disclosed
WO-2005063869-A1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORPORATION (US) 2005-07-14 WO disclosed
US-20050137311-A1 Flame retardant compositions and their use ALBEMARLE CORPORATION 2005-06-23 US disclosed