SCHEMBL4814244

SCHEMBL4814244

CS(=O)(=O)CCS(=O)(=O)C1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA7 P43166 1/20 0.30
CA14 Q9ULX7 1/20 0.30
NLRP3 Q96P20 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24017647 0.85 ALDH1A1 (0.33)
SCHEMBL777574 0.78 CA1 (0.33) CA12CA1CA7CA14
SCHEMBL9341953 0.77 CA12 (0.30) CA12CA1CA7CA14
SCHEMBL8134289 0.76 MMP1 (0.33) CA12CA1CA7
SCHEMBL2951024 0.76 CA1 (0.32) CA12CA1CA7CA14
SCHEMBL9341958 0.76
SCHEMBL23149821 0.76 CYP1A2 (0.41)
SCHEMBL778401 0.75 MMP1 (0.35) CA12CA1CA7CA14
SCHEMBL778711 0.75 ALOX5AP (0.31)
SCHEMBL8142390 0.74 CA12 (0.33) CA12CA1CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE40211-E1 Diazodisulfones WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2008-04-01 US disclosed
EP-0440375-B1 Diazodisulfones WAKO PURE CHEM IND LTD (JP) 1994-07-13 EP disclosed
US-5216135-A Photosensitive material which generates an acid by irradiation ; high transmittance, solution stability in photoresists and dissolution inhibiting of photoresists in alkali developers WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1993-06-01 US disclosed
EP-0440375-A1 Diazodisulfones WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1991-08-07 EP disclosed