Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4815087 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1LMNARAB9AMAPK1 | |
| SCHEMBL5408071 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1LMNARAB9AMAPK1 | |
| SCHEMBL14163363 | 0.91 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNARAB9AMAPK1 | |
| SCHEMBL10644154 | 0.90 | ALDH1A1 (0.58) | KDM4EALDH1A1LMNARAB9AMAPK1 | |
| SCHEMBL14400776 | 0.89 | ALDH1A1 (0.46) | KDM4EALDH1A1LMNARAB9AMAPK1 | |
| SCHEMBL4807659 | 0.89 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNARAB9AMAPK1 | |
| SCHEMBL4807663 | 0.89 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNARAB9AMAPK1 | |
| SCHEMBL14163398 | 0.89 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNARAB9AMAPK1 | |
| SCHEMBL4813060 | 0.88 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNARAB9AMAPK1 | |
| SCHEMBL4813058 | 0.88 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNARAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390916-B2 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2008-06-24 | — | — | US | disclosed |
| US-7390916-B2 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2008-06-24 | — | — | US | disclosed |
| US-20070249853-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2007-10-25 | — | — | US | disclosed |
| US-20070249853-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2007-10-25 | — | — | US | disclosed |
| US-7255853-B2 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2007-08-14 | — | — | US | disclosed |
| US-7255853-B2 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2007-08-14 | — | — | US | disclosed |
| US-20040175337-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2004-09-09 | — | — | US | disclosed |
| US-6749839-B2 | TOPICAL SUNSCREENS FOR HAIR OR SKIN | L'OREAL (FR) | 2004-06-15 | — | — | US | disclosed |
| US-20030031691-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040175337-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | CBR3, CBR1, H1-10 | KDM4E 1252/4885ALDH1A1 812/4885LMNA 3014/4885 |
| US-20030031691-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | CBR3, CBR1, NAA50 | KDM4E 1250/4885ALDH1A1 770/4885LMNA 2803/4885 |
| US-20070249853-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | CBR3, C1R, H1-3 | KDM4E 1910/4885ALDH1A1 1614/4885LMNA 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.