Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17073950 | 1.00 | CYP2C19 (0.46) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL1993737 | 1.00 | CYP2C19 (0.46) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL5917759 | 0.98 | NAAA (0.43) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL22615795 | 0.94 | NAAA (0.40) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL28676203 | 0.91 | CYP2C19 (0.40) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL22615739 | 0.91 | CYP2C19 (0.40) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL22616077 | 0.91 | CYP2C19 (0.40) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL9354748 | 0.89 | EPHX1 (0.46) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL22615477 | 0.89 | NAAA (0.46) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL21266113 | 0.89 | NAAA (0.46) | CYP2C19NAAAEPHX1HTTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12390437-B2 | Itaconic acid derivatives and uses thereof intreating an inflammatory disease or a disease associated with an undesirable immune response | SITRYX THERAPEUTICS LIMITED (GB) | 2025-08-19 | — | — | US | claimed |
| US-20240010891-A1 | ADHESIVE TWO-COMPONENT COMPOSITION BASED ON ITACONATE MONOMER | BOSTIK SA (FR) | 2024-01-11 | — | — | US | claimed |
| EP-4255945-A1 | ADHESIVE TWO-COMPONENT COMPOSITION BASED ON ITACONATE MONOMER | Bostik SA (FR) | 2023-10-11 | — | — | EP | claimed |
| CN-116472297-A | Two-component adhesive compositions based on itaconate monomers | 博斯蒂克股份公司 | 2023-07-21 | — | — | CN | claimed |
| US-20220265595-A1 | ITACONIC ACID DERIVATIVES AND USES THEREOF INTREATING AN INFLAMMATORY DISEASE OR A DISEASE ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-08-25 | — | — | US | claimed |
| WO-2022117940-A1 | ADHESIVE TWO-COMPONENT COMPOSITION BASED ON ITACONATE MONOMER | BOSTIK SA (FR) | 2022-06-09 | — | — | WO | claimed |
| WO-2022058473-A1 | PROCESS FOR PRODUCING FREE-RADICALLY CURABLE COMPOSITIONS BASED ON NOVEL REACTIVE DILUENTS AND REACTIVE DILUENTS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2022-03-24 | — | — | WO | claimed |
| EP-3962888-A1 | ITACONIC ACID DERIVATIVES AND USES THEREOF IN TREATING AN INFLAMMATORY DISEASE OR A DISEASE ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | Sitryx Therapeutics Limited (GB) | 2022-03-09 | — | — | EP | claimed |
| CN-113825740-A | Itaconic acid derivatives and their use in the treatment of inflammatory diseases or diseases associated with adverse immune reactions | 西特瑞治疗有限公司 | 2021-12-21 | — | — | CN | claimed |
| WO-2020222011-A1 | ITACONIC ACID DERIVATIVES AND USES THEREOF IN TREATING AN INFLAMMATORY DISEASE OR A DISEASE ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LIMITED (GB) | 2020-11-05 | — | — | WO | claimed |
| US-5563290-A | Method for preparing optically active succinic acid compound | NIPPON OIL CO. LTD. (JP) | 1996-10-08 | — | — | US | claimed |
| US-5093447-A | Contact lenses | NOVICKY NICK N (CA) | 1992-03-03 | — | — | US | claimed |
| US-4861850-A | CONTACT LENSES | PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) | 1989-08-29 | — | — | US | claimed |
| US-4748224-A | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | Devou, Maureen J. (CA) | 1988-05-31 | — | — | US | claimed |
| EP-0231572-A2 | Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof | PROGRESSIVE OPTICAL RESEARCH LTD. (CA) | 1987-08-12 | — | — | EP | claimed |
| EP-3637512-B1 | SULFUR-CARBON MATERIAL COMPOSITE BODY, POSITIVE ELECTRODE MATERIAL FOR LITHIUM SULFUR SECONDARY BATTERIES, AND LITHIUM SULFUR SECONDARY BATTERY | SEKISUI CHEMICAL CO LTD (JP) | 2026-04-01 | — | — | EP | disclosed |
| US-12479947-B2 | Curable compositions useful for obtaining non-sensitizing cured products | ARKEMA FRANCE (FR) | 2025-11-25 | — | — | US | disclosed |
| WO-1982001553-A1 | CROSS-LINKED HYDROPHILIC POLYMERS | PATEL PRAVIN | 1982-05-13 | — | — | WO | disclosed |
| US-4288499-A | Polymers adherent to polyolefins | ROHM AND HAAS COMPANY (US) | 1981-09-08 | — | — | US | disclosed |
| EP-0018847-A1 | Polyolefins having addition polymer adherent thereto, their preparation and articles comprising them | ROHM AND HAAS COMPANY (US) | 1980-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220265595-A1 | ITACONIC ACID DERIVATIVES AND USES THEREOF INTREATING AN INFLAMMATORY DISEASE OR A DISEASE ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | IL1R1, IL1B, IL1A | CYP2C19 2559/4885NAAA 3575/4885EPHX1 881/4885 |
| US-12390437-B2 | Itaconic acid derivatives and uses thereof intreating an inflammatory disease or a disease associated with an undesirable immune response | IL1R1, IL1B, IL1A | CYP2C19 2559/4885NAAA 3575/4885EPHX1 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.