SCHEMBL481575

SCHEMBL481575

C=CCOC(=O)C(C)=C(N)CC=C

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8985403 0.85 GLO1 (0.41) MAPTTSHRALDH1A1HSD17B10HPGD
SCHEMBL8985405 0.85 TSHR (0.40) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL15641518 0.82 MAPT (0.43) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL29220303 0.82 TSHR (0.44) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL14938405 0.81
SCHEMBL28992616 0.81 TSHR (0.38) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL665773 0.81 TSHR (0.38) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL9615427 0.79 MAPT (0.41) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL28101040 0.79 TSHR (0.38) MAPTCACNA1BAPBA1TSHRCYP3A4
SCHEMBL655218 0.78 TSHR (0.41) MAPTCACNA1BAPBA1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1090750-A Polymeric anticalculus agents UNILEVER NV (NL) 1994-08-17 CN claimed
US-4476270-A Process for making high solids acrylic dispersion lacquer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-09 US claimed
US-4378445-A EXTERIOR FINISHES FOR AUTOMOBILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-03-29 US claimed
US-4255308-A A DISPERSION COMPRISING A BINDER OF A METHYL METHACRYLATE POLYMER, A DISPERSANT OF AN ACRYLIC TERPOLYMER, AND A GRAFT POLYMER OF THE TWO; FINISHES FOR CARS AND TRUCKS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-03-10 US claimed
US-4213886-A Treatment of aluminum flake to improve appearance of coating compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-22 US claimed
US-4168249-A REFINISHING AUTOMOBILE AND TRUCK BODIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-09-18 US claimed
US-4020216-A Coating composition for flexible substrates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-26 US claimed
EP-4213980-A1 AMINE MODIFIED POLYSACCHARIDE URETHANE/UREA MICROCAPSULES Encapsys, LLC (US) 2023-07-26 EP disclosed
US-11554093-B2 Acrylic hair fixative copolymers and compositions NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2023-01-17 US disclosed
WO-2022061103-A1 AMINE MODIFIED POLYSACCHARIDE URETHANE/UREA MICROCAPSULES ENCAPSYS, LLC (US) 2022-03-24 WO disclosed
EP-3101414-B1 ACRYLAMIDE-FREE ELECTROCHEMICAL MEASUREMENT APPARATUS WITH LANTHANIDE GLASS ELECTRODE PILOT CORPORATION KK (JP) 2020-09-02 EP disclosed
EP-3285884-B1 ACRYLIC HAIR FIXATIVE COPOLYMERS AND COMPOSITIONS AKZO NOBEL CHEMICALS INT BV (NL) 2019-07-10 EP disclosed
US-10145814-B2 Internal solution for reference electrode, reference electrode, and glass electrode KABUSHIKI KAISHA PILOT CORPORATION (JP) 2018-12-04 US disclosed
US-4476270-A Process for making high solids acrylic dispersion lacquer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-09 US disclosed
US-4476270-A Process for making high solids acrylic dispersion lacquer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-09 US disclosed
US-4378445-A EXTERIOR FINISHES FOR AUTOMOBILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-03-29 US disclosed
US-4378445-A EXTERIOR FINISHES FOR AUTOMOBILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-03-29 US disclosed
US-4168249-A REFINISHING AUTOMOBILE AND TRUCK BODIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-09-18 US disclosed
US-4168249-A REFINISHING AUTOMOBILE AND TRUCK BODIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-09-18 US disclosed
US-4020216-A Coating composition for flexible substrates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-26 US disclosed