SCHEMBL8985403

SCHEMBL8985403

C=CCC(N)=C(C)C(=O)OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.41
ALOX15 P16050 1/20 0.40
NPSR1 Q6W5P4 1/20 0.37
ALDH1A1 P00352 5/20 0.37
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 1/20 0.36
MAPT P10636 1/20 0.34
CYP2D6 P10635 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HPGD P15428 1/20 0.32
CYP2C9 P11712 1/20 0.32
THRB P10828 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL481575 0.85 MAPT (0.40) ALDH1A1HSD17B10TSHRMAPTHPGD
SCHEMBL14938405 0.81
SCHEMBL197551 0.79 GLO1 (0.42) GLO1ALOX15NPSR1ALDH1A1LMNA
SCHEMBL3358255 0.78 ALOX15 (0.48) GLO1ALOX15NPSR1ALDH1A1LMNA
SCHEMBL9003084 0.78 ALOX15 (0.48) GLO1ALOX15NPSR1ALDH1A1LMNA
SCHEMBL27752747 0.78 GLO1 (0.41) GLO1ALOX15NPSR1ALDH1A1LMNA
SCHEMBL11498619 0.76 ALOX15 (0.39) GLO1ALOX15NPSR1ALDH1A1LMNA
SCHEMBL1635822 0.76 TDP1 (0.38) ALOX15ALDH1A1LMNATSHR
SCHEMBL1201121 0.76 TDP1 (0.38) ALOX15ALDH1A1LMNATSHR
SCHEMBL3358247 0.75 ALOX15 (0.44) GLO1ALOX15NPSR1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5561264-A Liquid-type developing device MINOLTA CO., LTD. (JP) 1996-10-01 US disclosed
EP-0225097-B1 TWO COMPONENT COATING COMPOSITION OF AN ANHYDRIDE CONTAINING POLYMER AND A GLYCIDYL COMPONENT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-04-11 EP disclosed
EP-0225097-A2 Two component coating composition of an anhydride containing polymer and a glycidyl component E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-06-10 EP disclosed