SCHEMBL9615427

SCHEMBL9615427

C=CCOC(=O)/C(CC=C)=C(\N)CC=C

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
CYP3A4 P08684 1/20 0.35
TSHR P16473 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28101040 0.87 TSHR (0.38) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL9445038 0.83 MAPT (0.35) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL481575 0.79 MAPT (0.40) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL2936819 0.78 CYP3A4 (0.36) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL2938491 0.78 CYP3A4 (0.36) MAPTCACNA1BAPBA1CYP3A4TSHR
Hydrochloric Acid SCHEMBL15512738 0.76 TSHR (0.36) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL3264414 0.74 ALDH1A1 (0.35) TSHRALDH1A1
SCHEMBL5716647 0.74
SCHEMBL11498619 0.74 ALOX15 (0.39) MAPTTSHRALDH1A1HSD17B10
SCHEMBL177943 0.73 CYP3A4 (0.48) MAPTCACNA1BAPBA1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4134055-A None JP disclosed
JP-H04134055-A DIALKYLAMINOACRYLIC ACID ALLYL ESTER AND PRODUCTION THEREOF UBE IND LTD 1992-05-07 JP disclosed