T-817

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	T-817 SCHEMBL48161	1.00	SIGMAR1 (0.83)	SIGMAR1OPRM1OPRK1CYP2A6HCRTR1
	T-817 SCHEMBL30574118	0.91	SIGMAR1 (1.00)	SIGMAR1OPRM1OPRK1CYP2A6HCRTR1
	T-817 SCHEMBL27725	0.91	SIGMAR1 (1.00)	SIGMAR1OPRM1OPRK1CYP2A6HCRTR1
	T-817 SCHEMBL4134384	0.90	SIGMAR1 (0.86)	SIGMAR1OPRM1OPRK1CYP2A6HCRTR1
	T-817 SCHEMBL47926	0.90	SIGMAR1 (0.98)	SIGMAR1OPRM1OPRK1CYP2A6HCRTR1
	T-817 SCHEMBL29371335	0.89	SIGMAR1 (1.00)	SIGMAR1OPRM1OPRK1CYP2A6
	T-817 SCHEMBL47995	0.89	SIGMAR1 (1.00)	SIGMAR1OPRM1OPRK1CYP2A6
	T-817 SCHEMBL48064	0.89	SIGMAR1 (1.00)	SIGMAR1OPRM1OPRK1CYP2A6
	T-817 SCHEMBL47997	0.89	SIGMAR1 (1.00)	SIGMAR1OPRM1OPRK1CYP2A6
	SCHEMBL27025	0.87	SIGMAR1 (0.91)	SIGMAR1OPRM1OPRK1CYP2A6HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.