Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | GBA1 | P04062 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15113191 | 0.87 | RXFP1 (0.73) | MEN1KMT2ASMN1; SMN2POLBLMNA | |
| SCHEMBL6824475 | 0.79 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2POLBGLA | |
| SCHEMBL5835697 | 0.77 | LMNA (0.68) | MEN1KMT2ASMN1; SMN2GLALMNA | |
| SCHEMBL3223685 | 0.76 | RAB9A (1.00) | MEN1KMT2ASMN1; SMN2POLBLMNA | |
| SCHEMBL404981 | 0.76 | RAB9A (0.75) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL18094513 | 0.75 | CA12 (0.56) | MEN1KMT2ASMN1; SMN2POLBGLA | |
| SCHEMBL2657289 | 0.74 | RAB9A (0.57) | MEN1KMT2ASMN1; SMN2POLBGLA | |
| SCHEMBL4749598 | 0.74 | LMNA (0.66) | MEN1KMT2ASMN1; SMN2POLBGLA | |
| SCHEMBL28424355 | 0.74 | POLB (0.55) | MEN1KMT2ASMN1; SMN2POLBGLA | |
| SCHEMBL2657198 | 0.74 | GCK (0.78) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |