Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425742 | 0.88 | PNMT (0.58) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL29892750 | 0.88 | PNMT (0.58) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL1830397 | 0.88 | PNMT (0.57) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL1830400 | 0.87 | PNMT (0.55) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL8671794 | 0.87 | PNMT (0.55) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL8473291 | 0.85 | PNMT (0.54) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL8473288 | 0.85 | PNMT (0.54) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL135489 | 0.85 | PNMT (0.54) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL6502789 | 0.85 | PNMT (0.54) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL7699409 | 0.85 | PNMT (0.54) | PNMTHTR2BHTR7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384754-B2 | Enrichment and tagging of glycosylated proteins | AGILENT TECHNOLOGIES, INC. (US) | 2008-06-10 | — | — | US | disclosed |
| US-7208573-B2 | Enrichment of phosphate peptides for proteomic analysis | AGILENT TECHNOLOGIES, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-20050095725-A1 | Enrichment of phosphate peptides for proteomic analysis | AGILENT TECHNOLOGIES, INC. | 2005-05-05 | — | — | US | disclosed |
| US-20050095647-A1 | Enrichment and tagging of glycosylated proteins | AGILENT TECHNOLOGIES, INC. | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050095725-A1 | Enrichment of phosphate peptides for proteomic analysis | PTMS, ACP1, CHAMP1 | PNMT 3696/4885HTR2B 4440/4885HTR7 4309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.