SCHEMBL4816746

SCHEMBL4816746

O=[N+]([O-])c1ccc(OP(=O)(O)O)c(Br)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
INPPL1 O15357 4/20 0.43
INPP5A Q14642 3/20 0.43
AKT1 P31749 1/20 0.43
INPP5B P32019 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
AKR1C3 P42330 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HTT P42858 1/20 0.39
ALDH1A1 P00352 2/20 0.39
GPR35 Q9HC97 2/20 0.39
MAPT P10636 2/20 0.39
CYP3A4 P08684 1/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064128 0.85 CA1 (0.61) CA1CA2CES2CES1INPPL1
SCHEMBL6041195 0.82 CA1 (0.57) CA1CA2CES2CES1INPPL1
SCHEMBL6041202 0.82 CA1 (0.57) CA1CA2CES2CES1INPPL1
SCHEMBL4823831 0.81 CA1 (0.56) CA1CA2CES2CES1INPPL1
SCHEMBL4535386 0.81 CA1 (0.56) CA1CA2CES2CES1MEN1
SCHEMBL1134003 0.81 CA1 (0.56) CA1CA2CES2CES1MEN1
SCHEMBL13980850 0.81 CA1 (0.56) CA1CA2CES2CES1INPPL1
SCHEMBL8900704 0.81 CA1 (0.56) CA1CA2CES2CES1INPPL1
SCHEMBL28734906 0.79 CA1 (0.54) CA1CA2CES2CES1MEN1
SCHEMBL29683621 0.79 HSPB1 (0.49) TDP1MEN1KMT2AL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7465556-B2 Method of immunoassay tartrate resistant acid phosphatase 5b and kit to be used therein NITTO BOSEKI CO., LTD. (JP) 2008-12-16 US disclosed
EP-1598670-B1 METHOD OF IMMUNOASSAYING TARTRATE RESISTANT ACID PHOSPHATASE 5b AND KIT TO BE USED THEREIN NITTO BOSEKI CO LTD (JP) 2007-06-20 EP disclosed
US-20060154317-A1 Method of immunoassaying taritrate resistant acid phosphatase 5b and kit to be used therein NITTO BOSEKI CO., LTD (JP) 2006-07-13 US disclosed
EP-1598670-A1 METHOD OF IMMUNOASSAYING TARTRATE RESISTANT ACID PHOSPHATASE 5b AND KIT TO BE USED THEREIN NITTO BOSEKI CO., LTD. (JP) 2005-11-23 EP disclosed