Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | INPPL1 | O15357 | 5/20 | 0.46 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | INPP5B | P32019 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064128 | 0.85 | CA1 (0.61) | CA1CA2CES2CES1INPPL1 | |
| SCHEMBL6041202 | 0.82 | CA1 (0.57) | CA1CA2CES2CES1INPPL1 | |
| SCHEMBL6041195 | 0.82 | CA1 (0.57) | CA1CA2CES2CES1INPPL1 | |
| SCHEMBL13980850 | 0.81 | CA1 (0.56) | CA1CA2CES2CES1INPPL1 | |
| SCHEMBL4535386 | 0.81 | CA1 (0.56) | CA1CA2CES2CES1SMN1; SMN2 | |
| SCHEMBL1134003 | 0.81 | CA1 (0.56) | CA1CA2CES2CES1SMN1; SMN2 | |
| SCHEMBL4816746 | 0.81 | CA1 (0.56) | CA1CA2CES2CES1INPPL1 | |
| SCHEMBL4823831 | 0.81 | CA1 (0.56) | CA1CA2CES2CES1INPPL1 | |
| SCHEMBL28734906 | 0.79 | CA1 (0.54) | CA1CA2CES2CES1SMN1; SMN2 | |
| SCHEMBL901296 | 0.78 | CA1 (0.53) | CA1CA2CES2CES1INPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481089-B1 | HUMAN MONOCLONAL ANTIBODY AGAINST GLYCOPROTEIN GP III OF VARICELLA ZOSTER VIRUS | TEIJIN LTD (JP) | 1997-07-30 | — | — | EP | disclosed |
| US-5650319-A | VIRICIDES AND ANTIBODIES | TEIJIN LIMITED (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0421382-B1 | Monoclonal antibody to exotoxin A of pseudomonas aeruginosa | SUMITOMO PHARMA (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0481089-A1 | HUMAN MONOCLONAL ANTIBODY AGAINST GLYCOPROTEIN GP III OF VARICELLA ZOSTER VIRUS | TEIJIN LIMITED (JP) | 1992-04-22 | — | — | EP | disclosed |
| EP-0421382-A1 | Monoclonal antibody to exotoxin A of pseudomonas aeruginosa | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-04-10 | — | — | EP | disclosed |